Last updated on August 2020

Evaluation for NCI Surgery Branch Clinical Research Protocols

Brief description of study


The National Cancer Institute Surgery Branch (NCI-SB) has developed experimental therapies that involve taking white blood cells from patients' tumor or from their blood, growing them in the laboratory in large numbers, and then giving the cells back to the patient.


This study will allow patients to under screening and evaluation for participation in NC-SB Protocols.


Patients 18 years or older must meet the minimum eligibility criteria for an NCI-SB treatment protocol.


Patients will undergo testing and evaluations as required by the appropriate NCI-SB treatment protocol.

Detailed Study Description


Potential research candidates undergo thorough screening including laboratory tests, scans, x-rays, and review of pathology slides to determine initial eligibility for National Cancer Institute Surgery Branch (NCI-SB) research protocols.


Permit evaluation of patients referred to the NCI-SB in order to identify individuals who will be suitable candidates for NCI-SB clinical research protocols.

To assess frequency of HLA type, gene specific mutations or expression of neo antigens in malignant tumors across the population of cancer patients undergoing screening for NCI-SB protocols.

Collect results of screening tests for use on subsequent research protocol as baseline (e.g., pretreatment) values.


Age >= 18 years and <= 70 years.

Patient suspected of having, or with biopsy proven, malignant disease.

Patient is able to understand and willing to sign a written informed consent document.

Patient is being evaluated for treatment on an NCI-SB protocols..


Patients enrolled on this protocol will be evaluated by NCI-SB physicians to determine the individual's suitability for participation in a clinical research protocol. An accrual ceiling of 6000 patients has been set to meet the screening needs of the NCI-SB.

Clinical Study Identifier: NCT00001823

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Recruitment Status: Open

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