Evaluation for NCI Surgery Branch Clinical Research Protocols

  • participants needed
  • sponsor
    National Cancer Institute (NCI)
Updated on 24 October 2022
white blood cell count



The National Cancer Institute Surgery Branch (NCI-SB) has developed experimental therapies that involve taking white blood cells from patients' tumor or from their blood, growing them in the laboratory in large numbers, and then giving the cells back to the patient.


This study will allow patients to under screening and evaluation for participation in NC-SB Protocols.


Patients 18 years or older must meet the minimum eligibility criteria for an NCI-SB treatment protocol.


Patients will undergo testing and evaluations as required by the appropriate NCI-SB treatment protocol.



Potential research candidates undergo thorough screening including laboratory tests, scans, x-rays, and review of pathology slides to determine initial eligibility for National Cancer Institute Surgery Branch (NCI-SB) research protocols.


Permit evaluation of patients referred to the NCI-SB in order to identify individuals who will be suitable candidates for NCI-SB clinical research protocols.

To assess frequency of HLA type, gene specific mutations or expression of neo antigens in malignant tumors across the population of cancer patients undergoing screening for NCI-SB protocols.

Collect results of screening tests for use on subsequent research protocol as baseline (e.g., pretreatment) values.


Age >= 18 years.

Patient suspected of having, or with biopsy proven, malignant disease.

Patient is able to understand and willing to sign a written informed consent document.

Patient is being evaluated for treatment on an NCI-SB protocols..


Patients enrolled on this protocol will be evaluated by NCI-SB physicians to determine the individual's suitability for participation in a clinical research protocol. An accrual ceiling of 7,000 patients has been set to meet the screening needs of the NCI-SB.

Condition Synovial Cell Cancer, Melanoma, Colorectal Cancer, Lung Cancer, Bladder Cancer
Clinical Study IdentifierNCT00001823
SponsorNational Cancer Institute (NCI)
Last Modified on24 October 2022


Yes No Not Sure

Inclusion Criteria

Age >= 18 years
Patient suspected of having, or with biopsy proven, malignant disease
Patient is able to understand and willing to sign a written informed consent
Patient is being evaluated for treatment on an NCI-SB protocols

Exclusion Criteria

Women of child-bearing potential who are pregnant or plan to become pregnant because of the
potentially dangerous effects of some of the screening procedures (e.g., nuclear medicine
or other imaging scans) on the fetus
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How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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