Adjuvant Radiotherapy for Stage II/III Thymoma After Complete Resection

  • End date
    Dec 22, 2029
  • participants needed
  • sponsor
    Fudan University
Updated on 22 January 2021
renal function
thymic neoplasm


This study is designed to investigate whether adjuvant radiotherapy after complete resection has a better survival for stage II or III thymoma.


It is confirmed by many studies that patients of thymoma with complete resection have better prognosis than those with either incomplete resection or without surgery. However,whether patients with stage II or III thymoma could benefit from adjuvant radiotherapy after complete resection remains controversial. The purpose of this study is to investigate whether adjuvant radiotherapy after complete resection can improve survival for stage II or III thymoma.

Condition Thymoma, Thymoma, Thymomas, thymic neoplasm
Treatment Adjuvant radiotherapy
Clinical Study IdentifierNCT02633553
SponsorFudan University
Last Modified on22 January 2021


Yes No Not Sure

Inclusion Criteria

~75 years old; Eastern Cooperative Oncology Group performance status of 0 to
Pathologically confirmed masaoka stage II or III thymoma; Have adequate
bone marrow, hepatic, and renal function; Patients receive complete resection
within 3 months; Written informed consent

Exclusion Criteria

Patients with distant metastases; Patients underwent radiotherapy or
chemotherapy; Patients who have malignancy history excluding carcinoma in situ
of cervix in the previous five years; Active clinical pulmonary infection
Pregnant or nursing
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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