Last updated on January 2019

Cisplatin Carboplatin and Etoposide or Temozolomide and Capecitabine in Treating Patients With Neuroendocrine Carcinoma of the Gastrointestinal Tract or Pancreas That Is Metastatic or Cannot Be Removed by Surgery


Brief description of study

This randomized phase II trial studies how well temozolomide and capecitabine work compared to standard treatment with cisplatin or carboplatin and etoposide in treating patients with neuroendocrine carcinoma of the gastrointestinal tract or pancreas that has spread to other parts of the body (metastatic) or cannot be removed by surgery. Drugs used in chemotherapy, such as temozolomide, capecitabine, cisplatin, carboplatin and etoposide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Certain types of neuroendocrine carcinomas may respond better to treatments other than the current standard treatment of cisplatin and etoposide. It is not yet known whether temozolomide and capecitabine may work better than cisplatin or carboplatin and etoposide in treating patients with this type of neuroendocrine carcinoma, called non-small cell neuroendocrine carcinoma.

Detailed Study Description

PRIMARY OBJECTIVES:

I. To assess the progression free survival (PFS) of platinum (cisplatin or carboplatin) and etoposide versus the PFS of temozolomide and capecitabine in patients with advanced G3 non-small cell gastroenteropancreatic neuroendocrine carcinomas.

SECONDARY OBJECTIVES:

I. To assess the response rate (RR) of platinum (cisplatin or carboplatin) and etoposide versus the RR of temozolomide and capecitabine in patients with advanced G3 non-small cell gastroenteropancreatic neuroendocrine carcinomas.

II. To assess the overall survival (OS) of platinum (cisplatin or carboplatin) and etoposide versus the OS of temozolomide and capecitabine in patients with advanced G3 non-small cell gastroenteropancreatic neuroendocrine carcinomas.

III. To evaluate the toxicities associated with the combination of temozolomide and capecitabine and the combination of platinum (cisplatin or carboplatin) and etoposide, respectively, in patients with advanced G3 non-small cell gastroenteropancreatic neuroendocrine carcinomas.

TERTIARY OBJECTIVES:

I. To assess the impact of each treatment regimen on PFS, RR and OS based on marker of proliferation Ki-67 index in patients with advanced G3 non-small cell gastroenteropancreatic neuroendocrine carcinomas. (Laboratory) II. To assess the prognostic significance of well differentiated versus poorly differentiated non-small cell gastroenteropancreatic neuroendocrine tumors in relationship to survival and response to treatment. (Laboratory) III. To assess the agreement in Ki-67 status between that reported by institutional pathologist and that reported by central pathology review. (Laboratory)

OUTLINE: Patients are randomized to 1 of 2 treatment arms.

ARM A: Patients receive capecitabine orally (PO) twice daily (BID) on days 1-14 and temozolomide PO once daily (QD) on days 10-14. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity.

ARM B: Patients receive cisplatin intravenously (IV) on days 1-3 or carboplatin IV on day 1. Patients also receive etoposide IV on days 1-3. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity.

After completion of study treatment, patients are followed up every 3 months for 2 years and then every 6 months for 3 years.

Clinical Study Identifier: NCT02595424

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Mehmet S. Copur

Mercy Cancer Center-Hot Springs
Hot Springs, AR United States
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Tatjana Kolevska

Kaiser Permanente-Deer Valley Medical Center
Antioch, CA United States
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Jorge A. Garcia-Young

Sutter Auburn Faith Hospital
Auburn, CA United States
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Jorge A. Garcia-Young

Sutter Cancer Centers Radiation Oncology Services-Auburn
Auburn, CA United States
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Jorge A. Garcia-Young

Alta Bates Summit Medical Center-Herrick Campus
Berkeley, CA United States
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Jorge A. Garcia-Young

Mills-Peninsula Medical Center
Burlingame, CA United States
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Jorge A. Garcia-Young

Sutter Cancer Centers Radiation Oncology Services-Cameron Park
Cameron Park, CA United States
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Jorge A. Garcia-Young

Eden Hospital Medical Center
Castro Valley, CA United States
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Jorge A. Garcia-Young

Sutter Davis Hospital
Davis, CA United States
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Tatjana Kolevska

Kaiser Permanente-Fremont
Fremont, CA United States
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Jorge A. Garcia-Young

Palo Alto Medical Foundation-Fremont
Fremont, CA United States
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Tatjana Kolevska

Kaiser Permanente
Fresno, CA United States
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Syma Iqbal

Los Angeles County-USC Medical Center
Los Angeles, CA United States
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Syma Iqbal

USC / Norris Comprehensive Cancer Center
Los Angeles, CA United States
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Andrew E. Hendifar

Cedars Sinai Medical Center
Los Angeles, CA United States
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Memorial Medical Center
Modesto, CA United States
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Tatjana Kolevska

Kaiser Permanente-Modesto
Modesto, CA United States
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Jorge A. Garcia-Young

Palo Alto Medical Foundation-Camino Division
Mountain View, CA United States
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Jorge A. Garcia-Young

Palo Alto Medical Foundation-Gynecologic Oncology
Mountain View, CA United States
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Syma Iqbal

USC Norris Oncology/Hematology-Newport Beach
Newport Beach, CA United States
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Jorge A. Garcia-Young

Sutter Cancer Research Consortium
Novato, CA United States
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Tatjana Kolevska

Kaiser Permanente-Oakland
Oakland, CA United States
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Jorge A. Garcia-Young

Palo Alto Medical Foundation Health Care
Palo Alto, CA United States
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Pamela L. Kunz

Stanford Cancer Institute
Palo Alto, CA United States
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Syma Iqbal

Keck Medical Center of USC Pasadena
Pasadena, CA United States
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Constantin A. Dasanu

Eisenhower Medical Center
Rancho Mirage, CA United States
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Tatjana Kolevska

Kaiser Permanente-Redwood City
Redwood City, CA United States
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Tatjana Kolevska

Kaiser Permanente-Richmond
Richmond, CA United States
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Tatjana Kolevska

Kaiser Permanente-Roseville
Roseville, CA United States
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Jorge A. Garcia-Young

Sutter Cancer Centers Radiation Oncology Services-Roseville
Roseville, CA United States
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Jorge A. Garcia-Young

Sutter Roseville Medical Center
Roseville, CA United States
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Jorge A. Garcia-Young

Sutter Medical Center Sacramento
Sacramento, CA United States
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Tatjana Kolevska

Kaiser Permanente-South Sacramento
Sacramento, CA United States
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Tatjana Kolevska

Kaiser Permanente - Sacramento
Sacramento, CA United States
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Jorge A. Garcia-Young

California Pacific Medical Center-Pacific Campus
San Francisco, CA United States
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Tatjana Kolevska

Kaiser Permanente-San Francisco
San Francisco, CA United States
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UCSF Medical Center-Mission Bay
San Francisco, CA United States
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Kaiser Permanente-Santa Teresa-San Jose
San Jose, CA United States
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Kaiser Permanente San Leandro
San Leandro, CA United States
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Kaiser Permanente-San Rafael
San Rafael, CA United States
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Kaiser Permanente Medical Center - Santa Clara
Santa Clara, CA United States
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Jorge A. Garcia-Young

Palo Alto Medical Foundation-Santa Cruz
Santa Cruz, CA United States
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Kaiser Permanente-Santa Rosa
Santa Rosa, CA United States
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Sutter Pacific Medical Foundation
Santa Rosa, CA United States
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Kaiser Permanente-South San Francisco
South San Francisco, CA United States
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Kaiser Permanente-Stockton
Stockton, CA United States
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Jorge A. Garcia-Young

Palo Alto Medical Foundation-Sunnyvale
Sunnyvale, CA United States
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Jorge A. Garcia-Young

Sutter Cancer Centers Radiation Oncology Services-Vacaville
Vacaville, CA United States
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Kaiser Permanente Medical Center-Vacaville
Vacaville, CA United States
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Kaiser Permanente-Vallejo
Vallejo, CA United States
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Jorge A. Garcia-Young

Sutter Solano Medical Center/Cancer Center
Vallejo, CA United States
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Tatjana Kolevska

Kaiser Permanente-Walnut Creek
Walnut Creek, CA United States
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Stephen Leong

University of Colorado Cancer Center - Anschutz Cancer Pavilion
Aurora, CO United States
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Mehmet S. Copur

Penrose-Saint Francis Healthcare
Colorado Springs, CO United States
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Mehmet S. Copur

Rocky Mountain Cancer Centers-Penrose
Colorado Springs, CO United States
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Porter Adventist Hospital
Denver, CO United States
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Mercy Medical Center
Durango, CO United States
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Southwest Oncology PC
Durango, CO United States
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Mountain Blue Cancer Care Center
Golden, CO United States
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Rocky Mountain Cancer Centers-Lakewood
Lakewood, CO United States
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Saint Anthony Hospital
Lakewood, CO United States
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Littleton Adventist Hospital
Littleton, CO United States
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Longmont United Hospital
Longmont, CO United States
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Rocky Mountain Cancer Centers-Longmont
Longmont, CO United States
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Parker Adventist Hospital
Parker, CO United States
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Rocky Mountain Cancer Centers-Parker
Parker, CO United States
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Saint Mary Corwin Medical Center
Pueblo, CO United States
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Rocky Mountain Cancer Centers - Pueblo
Pueblo, CO United States
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Mehmet S. Copur

Rocky Mountain Cancer Centers-Thornton
Thornton, CO United States
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Gregory A. Masters

Beebe Medical Center
Lewes, DE United States
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Christiana Gynecologic Oncology LLC
Newark, DE United States
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Gregory A. Masters

Delaware Clinical and Laboratory Physicians PA
Newark, DE United States
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Helen F Graham Cancer Center
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Medical Oncology Hematology Consultants PA
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Regional Hematology and Oncology PA
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Wilmington, DE United States
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Sibley Memorial Hospital
Washington, WA United States
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Kaiser Permanente Moanalua Medical Center
Honolulu, HI United States
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Kootenai Medical Center
Coeur d'Alene, ID United States
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Kootenai Cancer Center
Post Falls, ID United States
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Kootenai Cancer Clinic
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Rush - Copley Medical Center
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Illinois CancerCare-Bloomington
Bloomington, IL United States
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Memorial Hospital of Carbondale
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SIH Cancer Institute
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Centralia Oncology Clinic
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Al B. Benson

Northwestern University
Chicago, IL United States
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University of Chicago Comprehensive Cancer Center
Chicago, IL United States
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Carle on Vermilion
Danville, IL United States
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Cancer Care Center of Decatur
Decatur, IL United States
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Decatur Memorial Hospital
Decatur, IL United States
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Carle Physician Group-Effingham
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Crossroads Cancer Center
Effingham, IL United States
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Illinois CancerCare-Eureka
Eureka, IL United States
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Illinois CancerCare-Galesburg
Galesburg, IL United States
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Western Illinois Cancer Treatment Center
Galesburg, IL United States
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Illinois CancerCare-Kewanee Clinic
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Northwestern Medicine Lake Forest Hospital
Lake Forest, IL United States
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Illinois CancerCare-Macomb
Macomb, IL United States
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Carle Physician Group-Mattoon/Charleston
Mattoon, IL United States
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Good Samaritan Regional Health Center
Mount Vernon, IL United States
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UC Comprehensive Cancer Center at Silver Cross
New Lenox, IL United States
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University of Chicago Medicine-Orland Park
Orland Park, IL United States
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Illinois CancerCare-Ottawa Clinic
Ottawa, IL United States
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Radiation Oncology of Northern Illinois
Ottawa, IL United States
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Illinois CancerCare-Pekin
Pekin, IL United States
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OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center
Pekin, IL United States
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Methodist Medical Center of Illinois
Peoria, IL United States
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Illinois CancerCare-Peoria
Peoria, IL United States
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OSF Saint Francis Radiation Oncology at Peoria Cancer Center
Peoria, IL United States
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OSF Saint Francis Medical Center
Peoria, IL United States
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Illinois CancerCare-Peru
Peru, IL United States
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Valley Radiation Oncology
Peru, IL United States
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Illinois CancerCare-Princeton
Princeton, IL United States
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Central Illinois Hematology Oncology Center
Springfield, IL United States
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Southern Illinois University School of Medicine
Springfield, IL United States
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Springfield Clinic
Springfield, IL United States
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Memorial Medical Center
Springfield, IL United States
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Cancer Care Specialists of Illinois-Swansea
Swansea, IL United States
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Memorial and Saint Elizabeth's Health Care Services LLP
Swansea, IL United States
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Carle Cancer Center
Urbana, IL United States
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The Carle Foundation Hospital
Urbana, IL United States
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Rush-Copley Healthcare Center
Yorkville, IL United States
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Franciscan Saint Anthony Health-Michigan City
Michigan City, IN United States
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Woodland Cancer Care Center
Michigan City, IN United States
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Reid Health
Richmond, IN United States
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Mary Greeley Medical Center
Ames, IA United States
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McFarland Clinic PC-William R Bliss Cancer Center
Ames, IA United States
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McFarland Clinic PC-Boone
Boone, IA United States
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Mehmet S. Copur

Medical Oncology and Hematology Associates-West Des Moines
Clive, IA United States
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Mehmet S. Copur

Mercy Cancer Center-West Lakes
Clive, IA United States
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Mehmet S. Copur

Alegent Health Mercy Hospital
Council Bluffs, IA United States
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Mehmet S. Copur

Greater Regional Medical Center
Creston, IA United States
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Mehmet S. Copur

Medical Oncology and Hematology Associates-Laurel
Des Moines, IA United States
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Mehmet S. Copur

Mercy Medical Center - Des Moines
Des Moines, IA United States
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McFarland Clinic PC-Trinity Cancer Center
Fort Dodge, IA United States
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McFarland Clinic PC-Jefferson
Jefferson, IA United States
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Joseph J. Merchant

McFarland Clinic PC-Marshalltown
Marshalltown, IA United States
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Donald B. Wender

Siouxland Regional Cancer Center
Sioux City, IA United States
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Mehmet S. Copur

Mercy Medical Center-West Lakes
West Des Moines, IA United States
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Shaker R. Dakhil

Cancer Center of Kansas - Chanute
Chanute, KS United States
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Shaker R. Dakhil

Cancer Center of Kansas - Dodge City
Dodge City, KS United States
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Shaker R. Dakhil

Cancer Center of Kansas - El Dorado
El Dorado, KS United States
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Cancer Center of Kansas - Fort Scott
Fort Scott, KS United States
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Cancer Center of Kansas-Independence
Independence, KS United States
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Kingman, KS United States
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Liberal, KS United States
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Cancer Center of Kansas-Manhattan
Manhattan, KS United States
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Newton, KS United States
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Parsons, KS United States
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Pratt, KS United States
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Salina, KS United States
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Wellington, KS United States
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Associates In Womens Health
Wichita, KS United States
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Cancer Center of Kansas-Wichita Medical Arts Tower
Wichita, KS United States
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Via Christi Regional Medical Center
Wichita, KS United States
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Wichita NCI Community Oncology Research Program
Wichita, KS United States
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Cancer Center of Kansas - Winfield
Winfield, KS United States
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Mehmet S. Copur

Flaget Memorial Hospital
Bardstown, KY United States
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Mehmet S. Copur

Commonwealth Cancer Center-Corbin
Corbin, KY United States
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Oncology Hematology Care Inc-Crestview
Crestview Hills, KY United States
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Saint Joseph Radiation Oncology Resource Center
Lexington, KY United States
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Saint Joseph Hospital East
Lexington, KY United States
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Jewish Hospital
Louisville, KY United States
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Saints Mary and Elizabeth Hospital
Louisville, KY United States
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Jewish Hospital Medical Center Northeast
Louisville, KY United States
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Jewish Hospital Medical Center South
Shepherdsville, KY United States
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Ochsner Health Center-Summa
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Ochsner Medical Center Kenner
Kenner, LA United States
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University Health-Conway
Monroe, LA United States
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Ochsner Medical Center Jefferson
New Orleans, LA United States
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Louisiana State University Health Sciences Center Shreveport
Shreveport, LA United States
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Sinai Hospital of Baltimore
Baltimore, MD United States
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Johns Hopkins University/Sidney Kimmel Cancer Center
Baltimore, MD United States
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Northwest Hospital Center
Randallstown, MD United States
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William E Kahlert Regional Cancer Center/Sinai Hospital
Westminster, MD United States
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Massachusetts General Hospital Cancer Center
Boston, MA United States
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Beth Israel Deaconess Medical Center
Boston, MA United States
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Dana-Farber Cancer Institute
Boston, MA United States
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University of Michigan Comprehensive Cancer Center
Ann Arbor, MI United States
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Bronson Battle Creek
Battle Creek, MI United States
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Wayne State University/Karmanos Cancer Institute
Detroit, MI United States
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Weisberg Cancer Treatment Center
Farmington Hills, MI United States
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Mercy Health Saint Mary's
Grand Rapids, MI United States
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Grand Rapids, MI United States
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Kalamazoo, MI United States
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Bronson Methodist Hospital
Kalamazoo, MI United States
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West Michigan Cancer Center
Kalamazoo, MI United States
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Monroe Cancer Center
Monroe, MI United States
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Mercy Health Mercy Campus
Muskegon, MI United States
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Niles, MI United States
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Reed City, MI United States
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Lakeland Hospital
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Saint Joseph, MI United States
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Traverse City, MI United States
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Metro Health Hospital
Wyoming, MI United States
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Sanford Clinic North-Bemidgi
Bemidji, MN United States
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Fairview Ridges Hospital
Burnsville, MN United States
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Mercy Hospital
Coon Rapids, MN United States
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Edina, MN United States
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Fridley, MN United States
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Maple Grove, MN United States
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Maplewood, MN United States
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Saint John's Hospital - Healtheast
Maplewood, MN United States
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Abbott-Northwestern Hospital
Minneapolis, MN United States
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Hennepin County Medical Center
Minneapolis, MN United States
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Health Partners Inc
Minneapolis, MN United States
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New Ulm Medical Center
New Ulm, MN United States
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North Memorial Medical Health Center
Robbinsdale, MN United States
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Mayo Clinic
Rochester, MN United States
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Park Nicollet Clinic - Saint Louis Park
Saint Louis Park, MN United States
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Regions Hospital
Saint Paul, MN United States
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United Hospital
Saint Paul, MN United States
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Saint Francis Regional Medical Center
Shakopee, MN United States
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Lakeview Hospital
Stillwater, MN United States
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Waconia, MN United States
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Rice Memorial Hospital
Willmar, MN United States
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Minnesota Oncology Hematology PA-Woodbury
Woodbury, MN United States
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Fairview Lakes Medical Center
Wyoming, MN United States
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Saint Louis Cancer and Breast Institute-Ballwin
Ballwin, MO United States
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Central Care Cancer Center-Carrie J Babb Cancer Center
Bolivar, MO United States
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Parkland Health Center-Bonne Terre
Bonne Terre, MO United States
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CoxHealth Cancer Center
Branson, MO United States
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Saint Francis Medical Center
Cape Girardeau, MO United States
  Connect »

James L. Wade

Southeast Cancer Center
Cape Girardeau, MO United States
  Connect »

Barnes-Jewish West County Hospital
Creve Coeur, MO United States
  Connect »

James L. Wade

Capital Region Medical Center-Goldschmidt Cancer Center
Jefferson City, MO United States
  Connect »

Jay W. Carlson

Freeman Health System
Joplin, MO United States
  Connect »

Jay W. Carlson

Mercy Hospital-Joplin
Joplin, MO United States
  Connect »

Jay W. Carlson

Delbert Day Cancer Institute at PCRMC
Rolla, MO United States
  Connect »

Jay W. Carlson

Saint John's Clinic-Rolla-Cancer and Hematology
Rolla, MO United States
  Connect »

Jay W. Carlson

Heartland Regional Medical Center
Saint Joseph, MO United States
  Connect »

Jay W. Carlson

Saint Louis Cancer and Breast Institute-South City
Saint Louis, MO United States
  Connect »

Benjamin R. Tan

Washington University School of Medicine
Saint Louis, MO United States
  Connect »

Benjamin R. Tan

Siteman Cancer Center-South County
Saint Louis, MO United States
  Connect »

James L. Wade

Missouri Baptist Medical Center
Saint Louis, MO United States
  Connect »

Jay W. Carlson

Mercy Hospital Saint Louis
Saint Louis, MO United States
  Connect »

Siteman Cancer Center - Saint Peters
Saint Peters, MO United States
  Connect »

James L. Wade

Sainte Genevieve County Memorial Hospital
Sainte Genevieve, MO United States
  Connect »

Jay W. Carlson

Mercy Hospital Springfield
Springfield, MO United States
  Connect »

Jay W. Carlson

CoxHealth South Hospital
Springfield, MO United States
  Connect »

James L. Wade

Missouri Baptist Sullivan Hospital
Sullivan, MO United States
  Connect »

James L. Wade

Missouri Baptist Outpatient Center-Sunset Hills
Sunset Hills, MO United States
  Connect »

Jay W. Carlson

Mercy Hospital Washington
Washington, MO United States
  Connect »

Benjamin T. Marchello

Community Hospital of Anaconda
Anaconda, MT United States
  Connect »

Benjamin T. Marchello

Billings Clinic Cancer Center
Billings, MT United States
  Connect »

Saint Vincent Healthcare
Billings, MT United States
  Connect »

Benjamin T. Marchello

Bozeman Deaconess Hospital
Bozeman, MT United States
  Connect »

Saint James Community Hospital and Cancer Treatment Center
Butte, MT United States
  Connect »

Benjamin T. Marchello

Benefis Healthcare- Sletten Cancer Institute
Great Falls, MT United States
  Connect »

Benjamin T. Marchello

Great Falls Clinic
Great Falls, MT United States
  Connect »

Benjamin T. Marchello

Saint Peter's Community Hospital
Helena, MT United States
  Connect »

Benjamin T. Marchello

Kalispell Regional Medical Center
Kalispell, MT United States
  Connect »

Saint Patrick Hospital - Community Hospital
Missoula, MT United States
  Connect »

Benjamin T. Marchello

Community Medical Hospital
Missoula, MT United States
  Connect »

Mehmet S. Copur

CHI Health Saint Francis
Grand Island, NE United States
  Connect »

Mehmet S. Copur

Heartland Hematology and Oncology
Kearney, NE United States
  Connect »

Mehmet S. Copur

CHI Health Good Samaritan
Kearney, NE United States
  Connect »

Mehmet S. Copur

Saint Elizabeth Regional Medical Center
Lincoln, NE United States
  Connect »

Mehmet S. Copur

Alegent Health Immanuel Medical Center
Omaha, NE United States
  Connect »

Mehmet S. Copur

Hemotology and Oncology Consultants PC
Omaha, NE United States
  Connect »

Mehmet S. Copur

Alegent Health Bergan Mercy Medical Center
Omaha, NE United States
  Connect »

Mehmet S. Copur

Alegent Health Lakeside Hospital
Omaha, NE United States
  Connect »

Mehmet S. Copur

Creighton University Medical Center
Omaha, NE United States
  Connect »

Mehmet S. Copur

Midlands Community Hospital
Papillion, NE United States
  Connect »

Kathryn C. Hourdequin

Dartmouth Hitchcock Medical Center
Lebanon, NH United States
  Connect »

Omar Al Ustwani

Inspira Medical Center Vineland
Vineland, NJ United States
  Connect »

Carl J. Minniti

Inspira Medical Center Woodbury
Woodbury, NJ United States
  Connect »

Montefiore Medical Center-Einstein Campus
Bronx, NY United States
  Connect »

Montefiore Medical Center-Weiler Hospital
Bronx, NY United States
  Connect »

Montefiore Medical Center - Moses Campus
Bronx, NY United States
  Connect »

Raymond Thertulien

Asheville Hematology-Oncology Associates
Asheville, NC United States
  Connect »

James N. Atkins

Southeastern Medical Oncology Center-Clinton
Clinton, NC United States
  Connect »

Jeffrey Crawford

Duke University Medical Center
Durham, NC United States
  Connect »

James N. Atkins

Southeastern Medical Oncology Center-Goldsboro
Goldsboro, NC United States
  Connect »

James N. Atkins

Wayne Memorial Hospital
Goldsboro, NC United States
  Connect »

Raymond Thertulien

Park Ridge Hospital Breast Health Center
Hendersonville, NC United States
  Connect »

James N. Atkins

Onslow Memorial Hospital
Jacksonville, NC United States
  Connect »

James N. Atkins

Southeastern Medical Oncology Center-Jacksonville
Jacksonville, NC United States
  Connect »

Jeffrey Crawford

Duke Raleigh Hospital
Raleigh, NC United States
  Connect »

John J. Inzerillo

Marion L Shepard Cancer Center at Vidant Beaufort Hospital
Washington, NC United States
  Connect »

James N. Atkins

Southeastern Medical Oncology Center-Wilson
Wilson, NC United States
  Connect »

Preston D. Steen

Sanford Bismarck Medical Center
Bismarck, ND United States
  Connect »

Preston D. Steen

Roger Maris Cancer Center
Fargo, ND United States
  Connect »

Preston D. Steen

Sanford Broadway Medical Center
Fargo, ND United States
  Connect »

Preston D. Steen

Sanford Clinic North-Fargo
Fargo, ND United States
  Connect »

Jennifer R. Eads

UHHS-Chagrin Highlands Medical Center
Beachwood, OH United States
  Connect »

Timothy D. Moore

Strecker Cancer Center-Belpre
Belpre, OH United States
  Connect »

Howard M. Gross

Dayton Physicians LLC-Miami Valley South
Centerville, OH United States
  Connect »

Howard M. Gross

Miami Valley Hospital South
Centerville, OH United States
  Connect »

Jennifer R. Eads

Geaugra Hospital
Chardon, OH United States
  Connect »

Timothy D. Moore

Adena Regional Medical Center
Chillicothe, OH United States
  Connect »

Oncology Hematology Care Inc-Eden Park
Cincinnati, OH United States
  Connect »

Oncology Hematology Care Inc-Mercy West
Cincinnati, OH United States
  Connect »

Mehmet S. Copur

Good Samaritan Hospital - Cincinnati
Cincinnati, OH United States
  Connect »

Oncology Hematology Care Inc - Anderson
Cincinnati, OH United States
  Connect »

Howard M. Gross

Oncology Hematology Care Inc-Kenwood
Cincinnati, OH United States
  Connect »

Mehmet S. Copur

Bethesda North Hospital
Cincinnati, OH United States
  Connect »

Oncology Hematology Care Inc-Blue Ash
Cincinnati, OH United States
  Connect »

Mehmet S. Copur

TriHealth Cancer Institute-Westside
Cincinnati, OH United States
  Connect »

Mehmet S. Copur

TriHealth Cancer Institute-Anderson
Cincinnati, OH United States
  Connect »

Jennifer R. Eads

Case Western Reserve University
Cleveland, OH United States
  Connect »

Bruce J. Averbook

MetroHealth Medical Center
Cleveland, OH United States
  Connect »

Cleveland Clinic Cancer Center/Fairview Hospital
Cleveland, OH United States
  Connect »

Cleveland Clinic Foundation
Cleveland, OH United States
  Connect »

Manisha H. Shah

Ohio State University Comprehensive Cancer Center
Columbus, OH United States
  Connect »

Timothy D. Moore

Mount Carmel East Hospital
Columbus, OH United States
  Connect »

Timothy D. Moore

Columbus Oncology and Hematology Associates Inc
Columbus, OH United States
  Connect »

Timothy D. Moore

Riverside Methodist Hospital
Columbus, OH United States
  Connect »

Timothy D. Moore

Grant Medical Center
Columbus, OH United States
  Connect »

Timothy D. Moore

The Mark H Zangmeister Center
Columbus, OH United States
  Connect »

Timothy D. Moore

Mount Carmel Health Center West
Columbus, OH United States
  Connect »

Timothy D. Moore

Doctors Hospital
Columbus, OH United States
  Connect »

Howard M. Gross

Good Samaritan Hospital - Dayton
Dayton, OH United States
  Connect »

Howard M. Gross

Miami Valley Hospital
Dayton, OH United States
  Connect »

Howard M. Gross

Dayton Physicians LLC-Samaritan North
Dayton, OH United States
  Connect »

Howard M. Gross

Samaritan North Health Center
Dayton, OH United States
  Connect »

Timothy D. Moore

Delaware Health Center-Grady Cancer Center
Delaware, OH United States
  Connect »

Timothy D. Moore

Delaware Radiation Oncology
Delaware, OH United States
  Connect »

Timothy D. Moore

Grady Memorial Hospital
Delaware, OH United States
  Connect »

Jennifer R. Eads

Mercy Cancer Center-Elyria
Elyria, OH United States
  Connect »

Oncology Hematology Care Inc-Healthplex
Fairfield, OH United States
  Connect »

Howard M. Gross

Armes Family Cancer Center
Findlay, OH United States
  Connect »

Howard M. Gross

Blanchard Valley Hospital
Findlay, OH United States
  Connect »

Howard M. Gross

Orion Cancer Care
Findlay, OH United States
  Connect »

Howard M. Gross

Atrium Medical Center-Middletown Regional Hospital
Franklin, OH United States
  Connect »

Howard M. Gross

Dayton Physicians LLC-Atrium
Franklin, OH United States
  Connect »

Howard M. Gross

Dayton Physicians LLC-Wayne
Greenville, OH United States
  Connect »

Howard M. Gross

Wayne Hospital
Greenville, OH United States
  Connect »

Cleveland Clinic Cancer Center Independence
Independence, OH United States
  Connect »

Howard M. Gross

Greater Dayton Cancer Center
Kettering, OH United States
  Connect »

Howard M. Gross

First Dayton Cancer Care
Kettering, OH United States
  Connect »

Howard M. Gross

Kettering Medical Center
Kettering, OH United States
  Connect »

Timothy D. Moore

Fairfield Medical Center
Lancaster, OH United States
  Connect »

Timothy D. Moore

OhioHealth Mansfield Hospital
Mansfield, OH United States
  Connect »

Timothy D. Moore

Marietta Memorial Hospital
Marietta, OH United States
  Connect »

Timothy D. Moore

OneHealth Marion General Hospital
Marion, OH United States
  Connect »

Hillcrest Hospital Cancer Center
Mayfield Heights, OH United States
  Connect »

Jennifer R. Eads

Ireland Cancer Center Landerbrook Health Center
Mayfield Heights, OH United States
  Connect »

Jennifer R. Eads

Lake University Ireland Cancer Center
Mentor, OH United States
  Connect »

Jennifer R. Eads

Southwest General Health Center Ireland Cancer Center
Middleburg Heights, OH United States
  Connect »

Howard M. Gross

Dayton Physicians LLC-Signal Point
Middletown, OH United States
  Connect »

Timothy D. Moore

Knox Community Hospital
Mount Vernon, OH United States
  Connect »

Timothy D. Moore

Licking Memorial Hospital
Newark, OH United States
  Connect »

Timothy D. Moore

Newark Radiation Oncology
Newark, OH United States
  Connect »

Jennifer R. Eads

University Hospitals Parma Medical Center
Parma, OH United States
  Connect »

Timothy D. Moore

Southern Ohio Medical Center
Portsmouth, OH United States
  Connect »

Jennifer R. Eads

Ireland Cancer Center at Firelands Regional Medical Center
Sandusky, OH United States
  Connect »

North Coast Cancer Care
Sandusky, OH United States
  Connect »

Howard M. Gross

Dayton Physicians LLC-Wilson
Sidney, OH United States
  Connect »

Howard M. Gross

Springfield Regional Cancer Center
Springfield, OH United States
  Connect »

Howard M. Gross

Springfield Regional Medical Center
Springfield, OH United States
  Connect »

Cleveland Clinic Cancer Center Strongsville
Strongsville, OH United States
  Connect »

Jeffrey H. Muler

Flower Hospital
Sylvania, OH United States
  Connect »

Jeffrey H. Muler

The Toledo Hospital/Toledo Children's Hospital
Toledo, OH United States
  Connect »

Howard M. Gross

Dayton Physicians LLC-Upper Valley
Troy, OH United States
  Connect »

Howard M. Gross

Upper Valley Medical Center
Troy, OH United States
  Connect »

Jennifer R. Eads

University Hospitals Sharon Health Center
Wadsworth, OH United States
  Connect »

South Pointe Hospital
Warrensville Heights, OH United States
  Connect »

Timothy D. Moore

Saint Ann's Hospital
Westerville, OH United States
  Connect »

Jennifer R. Eads

UH-Seidman Cancer Center at Saint John Medical Center
Westlake, OH United States
  Connect »

Jennifer R. Eads

UHHS-Westlake Medical Center
Westlake, OH United States
  Connect »

Cleveland Clinic Wooster Family Health and Surgery Center
Wooster, OH United States
  Connect »

Timothy D. Moore

Genesis Healthcare System Cancer Care Center
Zanesville, OH United States
  Connect »

Hassan Hatoum

Cancer Centers of Southwest Oklahoma Research
Lawton, OK United States
  Connect »

Hassan Hatoum

University of Oklahoma Health Sciences Center
Oklahoma City, OK United States
  Connect »

Jay W. Carlson

Mercy Hospital Oklahoma City
Oklahoma City, OK United States
  Connect »

Nathan Bahary

UPMC-Heritage Valley Health System Beaver
Beaver, PA United States
  Connect »

Gregory A. Masters

Christiana Care Health System-Concord Health Center
Chadds Ford, PA United States
  Connect »

Raghava R. Levaka Veera

Geisinger Medical Center
Danville, PA United States
  Connect »

Nathan Bahary

UPMC Cancer Centers - Arnold Palmer Pavilion
Greensburg, PA United States
  Connect »

Raghava R. Levaka Veera

Geisinger Medical Center-Cancer Center Hazleton
Hazleton, PA United States
  Connect »

Nelson S. Yee

Penn State Milton S Hershey Medical Center
Hershey, PA United States
  Connect »

Nathan Bahary

UPMC-Johnstown/John P. Murtha Regional Cancer Center
Johnstown, PA United States
  Connect »

Raghava R. Levaka Veera

Geisinger Medical Oncology-Lewisburg
Lewisburg, PA United States
  Connect »

Raghava R. Levaka Veera

Lewistown Hospital
Lewistown, PA United States
  Connect »

Nathan Bahary

UPMC Cancer Center at UPMC McKeesport
McKeesport, PA United States
  Connect »

Nathan Bahary

UPMC-Coraopolis/Heritage Valley Radiation Oncology
Moon, PA United States
  Connect »

Peter J. O'Dwyer

University of Pennsylvania/Abramson Cancer Center
Philadelphia, PA United States
  Connect »

Fox Chase Cancer Center
Philadelphia, PA United States
  Connect »

Nathan Bahary

UPMC-Magee Womens Hospital
Pittsburgh, PA United States
  Connect »

Nathan Bahary

UPMC-Presbyterian Hospital
Pittsburgh, PA United States
  Connect »

Nathan Bahary

UPMC-Saint Margaret
Pittsburgh, PA United States
  Connect »

Nathan Bahary

University of Pittsburgh Cancer Institute (UPCI)
Pittsburgh, PA United States
  Connect »

Nathan Bahary

UPMC-Shadyside Hospital
Pittsburgh, PA United States
  Connect »

UPMC Jefferson Regional Radiation Oncology
Pittsburgh, PA United States
  Connect »

Nathan Bahary

UPMC-Passavant Hospital
Pittsburgh, PA United States
  Connect »

Nathan Bahary

UPMC-Saint Clair Hospital Cancer Center
Pittsburgh, PA United States
  Connect »

Raghava R. Levaka Veera

Geisinger Medical Oncology-Pottsville
Pottsville, PA United States
  Connect »

Raghava R. Levaka Veera

Community Medical Center
Scranton, PA United States
  Connect »

Raghava R. Levaka Veera

Geisinger Medical Oncology-Selinsgrove
Selinsgrove, PA United States
  Connect »

Nathan Bahary

UPMC Cancer Center at UPMC Northwest
Seneca, PA United States
  Connect »

Raghava R. Levaka Veera

Geisinger Medical Group
State College, PA United States
  Connect »

Nathan Bahary

UPMC Uniontown Hospital Radiation Oncology
Uniontown, PA United States
  Connect »

Nathan Bahary

UPMC Washington Hospital Radiation Oncology
Washington, PA United States
  Connect »

Raghava R. Levaka Veera

Geisinger Wyoming Valley/Henry Cancer Center
Wilkes-Barre, PA United States
  Connect »

Jay B. Nayak

AnMed Health Cancer Center
Anderson, SC United States
  Connect »

Medical University of South Carolina
Charleston, SC United States
  Connect »

Jeffrey K. Giguere

Greenville Health System Cancer Institute-Easley
Easley, SC United States
  Connect »

Jeffrey K. Giguere

Greenville Health System Cancer Institute-Butternut
Greenville, SC United States
  Connect »

Jeffrey K. Giguere

Greenville Health System Cancer Institute-Faris
Greenville, SC United States
  Connect »

Jeffrey K. Giguere

Greenville Memorial Hospital
Greenville, SC United States
  Connect »

Jeffrey K. Giguere

Greenville Health System Cancer Institute-Eastside
Greenville, SC United States
  Connect »

Jeffrey K. Giguere

Greenville Health System Cancer Institute-Greer
Greer, SC United States
  Connect »

Jeffrey K. Giguere

Greenville Health System Cancer Institute-Seneca
Seneca, SC United States
  Connect »

Jeffrey K. Giguere

Greenville Health System Cancer Institute-Spartanburg
Spartanburg, SC United States
  Connect »

Preston D. Steen

Sanford Cancer Center-Oncology Clinic
Sioux Falls, SD United States
  Connect »

Preston D. Steen

Sanford USD Medical Center - Sioux Falls
Sioux Falls, SD United States
  Connect »

Mehmet S. Copur

Memorial Hospital
Chattanooga, TN United States
  Connect »

Mehmet S. Copur

Pulmonary Medicine Center of Chattanooga-Hixson
Hixson, TN United States
  Connect »

Mehmet S. Copur

Memorial GYN Plus
Ooltewah, TN United States
  Connect »

Mehmet S. Copur

Saint Joseph Regional Cancer Center
Bryan, TX United States
  Connect »

Muhammad S. Beg

Parkland Memorial Hospital
Dallas, TX United States
  Connect »

Muhammad S. Beg

UT Southwestern/Simmons Cancer Center-Dallas
Dallas, TX United States
  Connect »

Muhammad S. Beg

UT Southwestern/Simmons Cancer Center-Fort Worth
Fort Worth, TX United States
  Connect »

Mehmet S. Copur

Harrison HealthPartners Hematology and Oncology-Bremerton
Bremerton, WA United States
  Connect »

Mehmet S. Copur

Harrison Medical Center
Bremerton, WA United States
  Connect »

Mehmet S. Copur

Highline Medical Center-Main Campus
Burien, WA United States
  Connect »

Mehmet S. Copur

Saint Elizabeth Hospital
Enumclaw, WA United States
  Connect »

Mehmet S. Copur

Saint Francis Hospital
Federal Way, WA United States
  Connect »

Mehmet S. Copur

Saint Clare Hospital
Lakewood, WA United States
  Connect »

Mehmet S. Copur

Harrison HealthPartners Hematology and Oncology-Poulsbo
Poulsbo, WA United States
  Connect »

Mehmet S. Copur

Franciscan Research Center-Northwest Medical Plaza
Tacoma, WA United States
  Connect »

Mehmet S. Copur

Northwest Medical Specialties PLLC
Tacoma, WA United States
  Connect »

Antony Ruggeri

Aurora Cancer Care-Southern Lakes VLCC
Burlington, WI United States
  Connect »

Richard J. Mercier

Marshfield Clinic-Chippewa Center
Chippewa Falls, WI United States
  Connect »

Richard J. Mercier

Marshfield Clinic Cancer Center at Sacred Heart
Eau Claire, WI United States
  Connect »

Antony Ruggeri

Aurora Health Center-Fond du Lac
Fond Du Lac, WI United States
  Connect »

Antony Ruggeri

Aurora Health Care Germantown Health Center
Germantown, WI United States
  Connect »

Antony Ruggeri

Aurora Cancer Care-Grafton
Grafton, WI United States
  Connect »

Antony Ruggeri

Aurora BayCare Medical Center
Green Bay, WI United States
  Connect »

Sam J. Lubner

UW Cancer Center Johnson Creek
Johnson Creek, WI United States
  Connect »

Antony Ruggeri

Aurora Cancer Care-Kenosha South
Kenosha, WI United States
  Connect »

Richard J. Mercier

Marshfield Clinic - Ladysmith Center
Ladysmith, WI United States
  Connect »

Sam J. Lubner

University of Wisconsin Hospital and Clinics
Madison, WI United States
  Connect »

Antony Ruggeri

Aurora Bay Area Medical Group-Marinette
Marinette, WI United States
  Connect »

Bay Area Medical Center
Marinette, WI United States
  Connect »

Antony Ruggeri

Vince Lombardi Cancer Clinic-Marinette
Marinette, WI United States
  Connect »

Richard J. Mercier

Marshfield Clinic
Marshfield, WI United States
  Connect »

Antony Ruggeri

Aurora Cancer Care-Milwaukee
Milwaukee, WI United States
  Connect »

Antony Ruggeri

Aurora Saint Luke's Medical Center
Milwaukee, WI United States
  Connect »

Ben George

Froedtert and the Medical College of Wisconsin
Milwaukee, WI United States
  Connect »

Antony Ruggeri

Aurora Sinai Medical Center
Milwaukee, WI United States
  Connect »

Richard J. Mercier

Marshfield Clinic-Minocqua Center
Minocqua, WI United States
  Connect »

David M. King

Cancer Center of Western Wisconsin
New Richmond, WI United States
  Connect »

Antony Ruggeri

Vince Lombardi Cancer Clinic - Oshkosh
Oshkosh, WI United States
  Connect »

Antony Ruggeri

Aurora Cancer Care-Racine
Racine, WI United States
  Connect »

Richard J. Mercier

Marshfield Clinic-Rice Lake Center
Rice Lake, WI United States
  Connect »

Antony Ruggeri

Vince Lombardi Cancer Clinic-Sheboygan
Sheboygan, WI United States
  Connect »

Marshfield Clinic Cancer Care at Saint Michael's Hospital
Stevens Point, WI United States
  Connect »

Richard J. Mercier

Marshfield Clinic Stevens Point Center
Stevens Point, WI United States
  Connect »

Antony Ruggeri

Aurora Medical Center in Summit
Summit, WI United States
  Connect »

Antony Ruggeri

Vince Lombardi Cancer Clinic-Two Rivers
Two Rivers, WI United States
  Connect »

Aurora Cancer Care-Waukesha
Waukesha, WI United States
  Connect »

Richard J. Mercier

Marshfield Clinic-Wausau Center
Wausau, WI United States
  Connect »

Antony Ruggeri

Aurora Cancer Care-Milwaukee West
Wauwatosa, WI United States
  Connect »

Antony Ruggeri

Aurora West Allis Medical Center
West Allis, WI United States
  Connect »

Richard J. Mercier

Marshfield Clinic - Weston Center
Weston, WI United States
  Connect »

Richard J. Mercier

Marshfield Clinic - Wisconsin Rapids Center
Wisconsin Rapids, WI United States
  Connect »

Big Horn Basin Cancer Center
Cody, WY United States
  Connect »

Benjamin T. Marchello

Billings Clinic-Cody
Cody, WY United States
  Connect »

Benjamin T. Marchello

Welch Cancer Center
Sheridan, WY United States
  Connect »

Recruitment Status: Open


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