Last updated on February 2020

LIquid BIopsies in Patients Presenting Non-small Cell Lung Cancer


Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Non-Small Cell Lung Cancer
  • Age: Between 18 - 100 Years
  • Gender: Male or Female

COHORT 1

Inclusion Criteria:

  • Patients with histologically confirmed advanced non-small-cell lung carcinoma (stage IIIB/IV) regardless of the mutation status
  • Inclusion at the time of diagnostic
  • Realization of tumor biopsy at the institution (Centre Lon Brard) or outside the institution with an available histopathological report
  • Age 18 years
  • Covered by a health insurance
  • Signed consent

Exclusion Criteria:

  • Patients treated before their liquid biopsy

COHORT 2 Inclusion criteria

  • Patients with histologically confirmed advanced non-small-cell lung carcinoma (stage IIIB/IV) with one of the following molecular anomalies: Epidermal Growth Factor Receptor (EGFR), B-Raf proto oncogene (BRAF) or Human Epidermal Growth Factor Receptor-2 (HER2) mutations, Anaplatsic Lymphoma Kinase (ALK) or ROS porto-oncogene 1 (ROS1) translocation, Mesenchymal-epithelial transition factor (MET) amplification, RET rearrangement.
  • Inclusion at the time of diagnosis
  • Realization of tumor biopsy at the institution (Centre Lon Brard) or outside the institution with an available histopathological report
  • Age 18 years
  • Covered by a health insurance
  • Signed consent

COHORT 3 Inclusion criteria

  • Patients with histologically confirmed advanced non-small-cell lung carcinoma (stage IIIB/IV) whatever the mutational or PD-L1 status.
  • Inclusion at the time of immunotherapy treatment initiation (1st or 2nd line)
  • Realization of tumor biopsy at the institution (Centre Lon Brard) or outside the institution with an available histopathological report
  • Age 18 years
  • Covered by a health insurance
  • Signed consent

Exclusion criteria

  • Initiation of immunotherpy before their liquid biopsy

Recruitment Status: Open


Brief Description Eligibility Contact Research Team


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