Adjuvant Treatment for Incomplete Resection Thymoma or Thymic Carcinoma

  • STATUS
    Recruiting
  • End date
    Dec 23, 2026
  • participants needed
    1
  • sponsor
    Fudan University
Updated on 23 January 2021
renal function
carcinoma
etoposide
thymic carcinoma
thymic neoplasm

Summary

This study is designed to investigate whether adjuvant radiochemotherapy after incomplete resection has a better survival than adjuvant radiotherapy for thymoma or thymic carcinoma.

Description

The previous trials have showed that radiotherapy was significantly associated with prolonged OS and chemotherapy is playing an increasing role in treatment of patients with thymoma or thymic carcinoma.However,whether patients with thymoma or thymic carcinoma could benefit from adjuvant radiochemotherapy after incomplete resection remains controversial. The purpose of this study is to investigate whether adjuvant radiochemotherapy after incomplete resection can improve survival for thymoma or thymic carcinoma.

Details
Condition Thymoma, Thymomas, thymic carcinoma
Treatment cisplatin, etoposide, Radiotherapy
Clinical Study IdentifierNCT02633514
SponsorFudan University
Last Modified on23 January 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

~75 years old; Eastern Cooperative Oncology Group performance status of 0 to
Pathologically confirmed ; incomplete resection (R1 or R2);have adequate
bone marrow, hepatic, and renal function;Patients receive incomplete resection
within 3 months; Written informed consent

Exclusion Criteria

Patients with distant metastases; Patients underwent radiotherapy or
chemotherapy; Patients who have malignancy history excluding carcinoma in situ
of cervix in the previous five years; Active clinical pulmonary infection
Pregnant or nursing
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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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