Last updated on June 2018

De Novo Lipogenesis of Sebaceous Glands in Acne


Brief description of study

There are two purposes of this study:

  1. First, the investigators want to see what the differences are in de novo sebaceous lipid production of people with and without acne.
  2. Secondly, the investigators want to know what happens to sebaceous gland de novo lipid production before and after treatment with topical tretinoin and oral isotretinoin.

Detailed Study Description

The primary objective of this study is to understand how de novo lipid production of sebaceous glands are altered in acne and with acne directed therapy.

Hypothesis 1: The overall de novo lipogenesis will be increased in those with acne

Hypothesis 2: Treatment with topical tretinoin and systemic isotretinoin will reduce de novo lipogenesis.

Clinical Study Identifier: NCT02620813

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Recruitment Status: Open


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