Treatment of Chronic Itch in Atopic Dermatitis (Eczema)

  • STATUS
    Not Recruiting
  • days left to enroll
    11
  • participants needed
    8
  • sponsor
    University of Minnesota
Updated on 20 October 2022

Summary

The purpose of this study is to assess the safety and efficacy of oral clonidine in subjects with symptomatic atopic dermatitis and to assess the safety and efficacy of oral naltrexone in subjects with symptomatic atopic dermatitis.

Description

This study will serve as a pilot study to determine the efficacy and safety of two novel oral agents (clonidine, naltrexone) in the treatment of chronic, non-experimentally induced itch in atopic dermatitis. In this study, eight subjects with symptomatic atopic dermatitis will be recruited and treated with either oral clonidine (four subjects) or oral naltrexone (four subjects) . Disease burden will be evaluated before and after 4 weeks of treatment through reporting of subjective symptomatology via surveys/questionnaire, neurometer study, and clinical assessment.

Details
Condition Cutaneous Nerves CNS Itch
Treatment naltrexone, clonidine
Clinical Study IdentifierNCT02268448
SponsorUniversity of Minnesota
Last Modified on20 October 2022

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