Effect of Hypoxia on Cognitive Assessment and Cerebral Activity in Healthy Volunteers

  • participants needed
  • sponsor
    University Hospital, Lille
Updated on 4 August 2021
Régis Bordet, MD,PhD
Primary Contact
Centre d'investigation Clinique (0.0 mi away) Contact
+1 other location
cognitive impairment


The early assessment of new symptomatic drugs for Alzheimer disease remains difficult because of the lack of predictive end-point. The use of a battery including different parameters could improve this early development. In healthy volunteers, to test the reverse effect of symptomatic drugs, it is necessary to induce transient and reversible cognitive impairment and cerebral activity changes by a challenge test. In this context, a transient hypoxia could be relevant.

Condition Hypoxia, Alteration of Cognitive Function, cognitive changes, hypoxic
Treatment 2-hour period of hypoxia
Clinical Study IdentifierNCT02891343
SponsorUniversity Hospital, Lille
Last Modified on4 August 2021

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