Last updated on November 2019

Evaluation of the Efficacy of Serotoninergic Antidepressants in Bulimia Nervosa According to Brain Serotonin Profile Determined by Positron Emission Tomography With [18F] MPPF.


Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Bulimia | Bulimia Nervosa
  • Age: Between 18 - 100 Years
  • Gender: Female

Inclusion Criteria:

  • Patient affiliated or entitled to a social security scheme
  • Bulimic patients according to DSM-IV TR: minimum 2 bulimic crises (compulsive eating followed by compensatory behavior) / week for 3 weeks
  • Patients who signed informed consent to the study
  • BMI greater than or equal to 18.5 kg / m

Exclusion Criteria:

  • Against-indication to the SSRI or fluoxetine
  • SSRI consumption in the previous three months
  • Other addiction (except tobacco, for reasons of feasibility)
  • Diagnosis of binge eating disorder or EDNOS (DSM-IV-TR)
  • Patients with heart failure
  • Against-indication for PET and / or MRI: pacemaker, intracerebral clips, prosthesis made of ferromagnetic material or claustrophobia
  • Subjects with suspected pregnancy or in the second half of their menstrual cycle in the absence of oral contraceptives; positive -HCG test before the exam

Recruitment Status: Open


Brief Description Eligibility Contact Research Team


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