Influence of Periodontal Diseases on Vascular Parameters in Patients Suffering of Hypertension

  • End date
    Aug 20, 2023
  • participants needed
  • sponsor
    University Hospital, Strasbourg, France
Updated on 20 September 2021
periodontal disease
chronic periodontitis


The aim of this study is to assess the influence of the severity of chronic periodontitis on hemodynamic parameters in hypertensive patients.Secondary purposes of this protocol is to identify evolution of several biomarkers and correlate the clinical situation with oral microflora.

Condition Periodontitis, Diabetes and Hypertension, High Blood Pressure (Hypertension), Elevated Blood Pressure, high blood pressure, High Blood Pressure (Hypertension - Pediatric), arterial hypertension, Vascular Diseases, Chronic Periodontitis, Hypertension
Treatment echo Doppler lower limbs
Clinical Study IdentifierNCT02394860
SponsorUniversity Hospital, Strasbourg, France
Last Modified on20 September 2021


Yes No Not Sure

Inclusion Criteria

Men- >40 years
moderate and severe generalized chronic periodontitis
Former diagnosis of hypertension
>12 teeth

Exclusion Criteria

>70 years
smokers (>10 cig/day)
body mass index>30
Need of antibioprophylaxis
Medical treatment including anti-inflammatory drugs and/or antibiotics
Refractory form of hypertension- aggressive periodontitis
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