Last updated on August 2018

Natural History of the Progression of Choroideremia Study

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Choroideremia
  • Age: Between 18 - 100 Years
  • Gender: Male

Inclusion Criteria:

  • Are willing and able to provide informed consent for participation in the study.
  • Are male and 18 years of age.
  • Have a clinical phenotype and confirmed genetic diagnosis of CHM.
  • Have active disease clinically visible within the macular region.
  • Are willing and able to undergo ophthalmic examinations once every 4 months for up to 20 months.
  • Have a BCVA better than or equal to 6/60 (20/200; decimal 0.1; LogMAR 1.0; 34-38 Early Treatment Diabetic Retinopathy Study [ETDRS] letters) in at least one eye.

Exclusion Criteria:

  • Have a history of amblyopia in the eligible eye.
  • Have any other significant ocular or non-ocular disease/disorder in the eligible eye which, in the opinion of the investigator, may put the subject at risk because of participation in the study, influence the results of the study or influence the subject's ability to participate in the study.
  • Have participated in an interventional research study in the past 6 months.

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

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