Last updated on January 2019

Randomized Embedded Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia

Brief description of study

The purpose of this study is to evaluate the effect of a range of interventions on patients admitted to intensive care with community-acquired pneumonia.

Detailed Study Description

Patients with pneumonia who are being treated in an ICU will receive many different treatments, as many as 20 or 30, that act together to treat both the infection and its effects on the body. When treating a patient, doctors choose from many different treatments, most of which are known or believed to be safe and effective. However, doctors don't always know which treatment option is the better one, as individuals or groups of individuals may respond differently. This study aims to help doctors understand which treatments work best.

This clinical study has been designed in a way that allows the information from patients already in the study to help new patients joining the study. Most studies aren't able to do that. REMAP-CAP has been designed to:

  • Test several treatments, at the same time, in the same patient.
  • Look at the results as it goes and uses these results so that new patients in the study have a better chance of getting better treatments
  • Drop treatments if they are shown to be less effective than others
  • Add new treatments to the study as those that have undergone testing complete their evaluation

Clinical Study Identifier: NCT02735707

Find a site near you

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Nepean Hospital

Sydney, Australia
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Logan Hospital

Brisbane, Australia
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Toowoomba Hospital

Toowoomba, Australia
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Bendigo Hospital

Bendigo, Australia
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The Alfred Hospital

Melbourne, Australia
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Cabrini Hospital

Melbourne, Australia
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North Shore Hospital

Auckland, New Zealand
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Middlemore Hospital

Auckland, New Zealand
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Christchurch Hospital

Christchurch, New Zealand
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Waikato Hospital

Hamilton, New Zealand
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Tauranga Hospital

Tauranga, New Zealand
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Recruitment Status: Open

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