Last updated on January 2019

Diffusion Weighted Magnetic Resonance in Imaging Younger Patients With Newly Diagnosed Bone or Soft Tissue Sarcomas

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Osteosarcoma | Rhabdomyosarcoma | Sarcoma | Ewing's sarcoma | Non-rhabdomyosarcoma Soft-tissue Sarcoma | Bone
  • Age: - 100 Years
  • Gender: Male or Female

Inclusion Criteria:

  • All St Jude patients with a known or suspected, newly diagnosed bone or soft-tissue sarcoma who will be treated on or as per disease specific protocols.
  • Study subjects will have undergone or are scheduled for PET-CT and/or bone scan within about 2 weeks of the WB and primary tumor DWI MRI.
  • No limit on age or gender
  • Informed consent or assent signed by study subject or parent/guardian according to institutional guidelines.
  • Patients should not have begun therapy, or, needed research imaging can be performed within 2-5 days of starting therapy.

Exclusion Criteria:

  • Subject has a tumor that will undergo upfront resection
  • Subject is unable or unwilling to follow study requirements, including signed consent or assent
  • Subject is hospitalized in the intensive care unit.
  • Subject does not meet institutional MRI safety screening requirements.
  • Subject has undergone primary tumor resection prior to arrival at St. Jude.
  • Subjects who require sedation for WB MRI will be excluded if they have:
  • An acute cardiopulmonary process including, but not limited to, croup, reactive airways disease, pneumonia, clinical or radiological evidence of pericardial effusion or other cardiopulmonary disease.
  • Vomiting within 24 hours of the MRI or substantial nausea that may preclude sedation as determined by the anesthesiologist or certified registered nurse anesthetist.

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

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