Last updated on November 2019

Impact of Combined Hormonal Contraceptives on UPA


Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Contraception
  • Age: Between 18 - 35 Years
  • Gender: Female

Inclusion Criteria:

  • Generally healthy women aged 18 to 35 with regular menses (every 21-35 days).
  • Normal BMI
  • Proven ovulation with a screening serum progesterone of >3ng/mL
  • Willing to use condoms (if sexually active with a male partner), willing to not have sex with men during the study, or have had a tubal ligation (or have a partner who has had a vasectomy) or have a copper intrauterine device (IUD).

Exclusion Criteria:

  • Known intolerance or allergy to any of the study medication
  • Known metabolic disorders including polycystic ovarian syndrome or uncontrolled thyroid disorder
  • Overweight or obese BMI
  • Any Centers for Disease Control and Prevention (CDC) Medical eligibility criteria category 3 or 4 for combined oral contraception (COC) use 12.
  • Pregnancy, breastfeeding, or seeking pregnancy; recent (8 week) use of hormonal contraception
  • Current use of drugs that interfere with metabolism of sex steroids
  • Smokers.

Recruitment Status: Closed


Brief Description Eligibility Contact Research Team


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