Last updated on August 2019

OPTimizing Irradiation Through Molecular Assessment of Lymph Node (OPTIMAL)

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Breast Cancer
  • Age: Between 18 - 100 Years
  • Gender: Female

Inclusion Criteria:

  1. Infiltrating, ductal carcinoma of the breast.
  2. Treated with conservative surgery (tumorectomy or quadrantectomy) without lymphadenectomy.
  3. Sentinel lymph node assessed by OSNA, with TTL in the range 250 - 15,000 copies/L.
  4. Age 18 yrs old.
  5. Karnofsky Index 70 %.
  6. Signed Informed Consent.

Exclusion Criteria:

  1. Other types of breast cancer different from infiltrating ductal carcinoma.
  2. Bilateral breast cancer.
  3. Males.
  4. Mastectomy or axillary homolateral lymph node dissection.
  5. Previous thoracic irradiation therapy.
  6. Systemic neoadjuvant therapy previous to surgery.
  7. Contraindications of radiotherapy (pregnancy, severe collagen diseases).
  8. Other neoplasms.
  9. Severe associated comorbidities that, according to the investigator criteria, may interfere with the study evaluations.

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

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