This study evaluates the effect of different induction courses in children and adolescents with newly diagnosed acute myeloid leukemia. In the first course patients are randomised to receive either standard anthracycline therapy with mitoxantrone or experimental DaunoXome. In the second course patients are randomised between standard treatment with ADxE (cytarabine, DaunoXome, etoposide) or experimental therapy with FLADx (fludarabine, cytarabine, DaunoXome).
| Condition | Pediatric Acute Myeloblastic Leukemia |
|---|---|
| Treatment | Randomisation course 1 mitoxantrone versus DaunoXome, Randomisation course 2 ADxE versus FLADx |
| Clinical Study Identifier | NCT01828489 |
| Sponsor | Vastra Gotaland Region |
| Last Modified on | 30 March 2023 |
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