Last updated on August 2018

Generalization of Extinction Learning

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Claustrophobia
  • Age: Between 18 - 55 Years
  • Gender: Male or Female

Inclusion Criteria:

  1. between the ages of 18 and 55,
  2. fluent in English,
  3. within normal body weight (BMI=18.5 to 24.9)
  4. meet DSM-IV diagnostic criteria for Social Phobia and report a fear of public speaking.

Exclusion Criteria:

  1. participant report of a diagnosed medical or neurological disorder
  2. prescription or over the counter medications that can interact with Scopolamine, such as anticholinergic medications (e.g. belladonna alkaloids, antihistamines, meclizine, tricyclic antidepressants, and muscle relaxants), cold medicines, cough suppressants. Other drugs that will be reasons for exclusion include: antimuscarinics, nifedipine, parasympathomimetics, amantadine, amoxapine, antacids, antidiarrheals, anxiolytics, hypnotics, atomexetine, bupropion, cisapride, clozapine, cyclobenzaprine, digoxin, disopyramide, dronabinol (THC), ethanol, maprotilline, memantine, metoclopramide, nabilone, olanzapine, opiate agonists, orphenadrine, phenothiazines, potassium salts, quinidine, sedating H1-blockers, topiramate, tricyclic antidepressants, erthyromycin, ketoconazole, and tegaserod.
  3. over the counter drugs or substances that may have a sedative effect (e.g. herbal sedatives: ashwagandha, Duboisia hopwoodii, Prostanthera striatiflora, kava, mandrake, valerian, cannabis, passiflora incarnate; Antihistamines: Diphenhydramine, Dimenhydrinate, Doxylamine, Promethazine; Alcohol; Dextromethorphan)
  4. individuals with urinary problems (e.g., BPH)
  5. pregnant or nursing females (as the effect of Scop on fetuses is not known)
  6. suicidality
  7. delusions or hallucinations
  8. history of substance dependence in last five years or substance abuse within the past 6 months

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

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