Last updated on March 2019

Adrenalectomy Versus Follow-up in Patients With Subclinical Cushings Syndrome


Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Adrenal Tumour With Mild Hypercortisolism
  • Age: Between 18 - 100 Years
  • Gender: Male or Female

Inclusion Criteria:

  • Adrenal tumour with biochemical mild hypercortisolism defined as pathological dexamethasone suppression test (cortisol > 50 nmol/L at 8.00 am after 1 mg dexamethasone at 10 pm, plus one of the following criteria
  • Low or suppressed adrenocorticotropic hormone (ACTH)
  • Low or suppressed dehydroepiandrosterone (DHEA)
  • No or pathological circadian rhythm of cortisol

Exclusion Criteria:

  • Increased levels of 24 hours urinary excretion of cortisol
  • Pregnancy or lactation
  • Inability to understand information or to comply with scheduled follow-up
  • Mild hypercortisolism with bilateral adrenal tumours, without a gradient (lateralization on venous sampling)

Recruitment Status: Open


Brief Description Eligibility Contact Research Team


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