Elucidating Kisspeptin Physiology by Blocking Kisspeptin Signaling
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- STATUS
- Recruiting
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- End date
- Sep 8, 2023
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- participants needed
- 411
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- sponsor
- Massachusetts General Hospital
Summary
The investigators are looking for subjects to complete a study on the role of kisspeptin in the reproductive system. Kisspeptin is a naturally occurring hormone in humans that tells the body to produce other reproductive hormones. However, giving someone a continued amount of kisspeptin over a period of time can have the opposite effect and tell the body to, for a short time, stop making hormones needed for reproduction. By giving 24-hour infusions of kisspeptin, the investigators hope to learn more about the role kisspeptin has in the way bodies function normally and the role it has in conditions that affect the reproductive system.
Description
Please contact study staff for a detailed description.
Details
| Condition | hypogonadotropic hypogonadism, Klinefelter's Syndrome, Agonadism, secondary hypogonadism, Primary Gonadal Insufficiency in Men, Healthy Postmenopausal Women, Hypogonadism, Hypergonadotropic Hypogonadism in Men, klinefelter syndrome |
|---|---|
| Treatment | kisspeptin 112-121, GnRH |
| Clinical Study Identifier | NCT01438073 |
| Sponsor | Massachusetts General Hospital |
| Last Modified on | 8 July 2021 |
Eligibility
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