Alzheimer's Disease Core Center (ADCC)

  • End date
    Jul 21, 2025
  • participants needed
  • sponsor
    University of Arizona
Updated on 25 January 2022
cognitive impairment
alzheimer's disease
mild cognitive impairment
cognitive disorder
Accepts healthy volunteers


The main objective of this research project is to provide a comprehensive clinical database of patients with Alzheimer's disease (AD) and other forms of dementia, individuals with mild cognitive impairment (MCI), and age-matched normal controls. The study will also attempt to identify cognitively normal individuals at genetically defined risk for Alzheimer's disease through genetic screening.

All participants are seen annually. Autopsies to establish diagnoses in patients with dementia, patients with mild MCI, and cognitively normal elderly control subjects will also be conducted.


All participants are seen annually. In addition to a detailed neurological examination, participants will receive a standardized battery of neuropsychological tests and will undergo genetic testing. The investigators will provide standardized periodic longitudinal assessment of the research participants. Autopsies to establish neurohistopathological diagnoses in clinically well-characterized patients with dementia, patients with mild MCI, and cognitively normal elderly control subjects will also be conducted.

Condition Alzheimer's Disease, Mild Cognitive Impairment, Age-Related Memory Disorders
Clinical Study IdentifierNCT01421420
SponsorUniversity of Arizona
Last Modified on25 January 2022


Yes No Not Sure

Inclusion Criteria

For patients with MCI, or dementia, the presence of cognitive deficits
including memory, language, and executive function

Exclusion Criteria

Presence of non-neurological medical conditions interfering with cognition
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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