Last updated on February 2018

Endothelial Function Study Before Cardiovascular Surgery


Brief description of study

The aim of this clinical trial is to evaluate the effect of chronic obstructive pulmonary disease (COPD) and/or obstructive sleep apnea syndrome (OSAS) on the endothelial function, before cardiovascular surgery, compared to non COPD non OSAS patients undergoing also a cardiovascular surgery, by an observational physiological study.

An interim analysis will be performed when 100 patients will be included.

Detailed Study Description

Secondary objectives of this clinical trial :

  • To evaluate the effect of COPD and/or OSAS on the systemic inflammation, insulin-resistance and oxydative stress, in comparison with non COPD non OSAS patients.
  • To evaluate the effect of COPD and/or OSAS on the inflammation and oxydative stress of the adipose tissue, in comparison with non COPD non OSAS patients.
  • To validate the STOP-BANG questionnaire in patients undergoing a cardiovascular surgery

Clinical Study Identifier: NCT01195064

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