Last updated on March 2019

Study of Progression of Community Acquired Pneumonia in the Hospital

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Pneumonia | Toxic Shock Syndrome | Septicemia
  • Age: Between 18 - 100 Years
  • Gender: Male or Female

Inclusion Criteria:

  1. Hospitalization with community acquired pneumonia (CAP) confirmed by pulmonary infiltrate in chest radiograph
  2. Working diagnosis of CAP by enrolling physician
  3. Adult patient >= 18 years of age
  4. Valid informed consent form
  5. At least 2 out of the five following clinical symptoms:
    • Fever
    • Cough
    • Purulent sputum
    • Shortness of breath or need for respiratory support
    • Crackling or rales on auscultation, dullness to percussion, or bronchial breathing

Exclusion Criteria:

  1. Participation in this study at an earlier time
  2. Hospitalization for any reason within 28 days prior to hospitalization for the current episode of CAP
  3. More than 48 hours in the hospital before enrollment
  4. Pregnancy
  5. Breastfeeding
  6. Decision on limitation of therapy before enrollment
  7. Known HIV infection or AIDS
  8. Anti-tumor treatment within the past six months
  9. Post-stenotic pneumonia in conjunction with bronchial carcinoma
  10. Therapy with corticosteroids 20mg for 14 days before enrollment
  11. Non-steroidal immunosuppressive therapy within the past six months
  12. Cytostatic therapy within the past six months
  13. Radiation therapy within the past six months
  14. Bone marrow transplant received
  15. Respiratory support at home via tracheostoma
  16. Cystic fibrosis
  17. Active tuberculosis
  18. Acute lung injury or acute respiratory distress syndrome for extrapulmonary reasons
  19. Massive aspiration
  20. Sepsis with extrapulmonary focus
  21. Acute pulmonary embolism
  22. Congestive heart failure New York Heart Association (NYHA) IV stadium
  23. Liver insufficiency Child-Pugh C stadium

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

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