Genomic Profiling in Cancer Patients
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- STATUS
- Recruiting
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- End date
- Jan 21, 2024
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- participants needed
- 200
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- sponsor
- Memorial Sloan Kettering Cancer Center
Summary
The purpose of this study is to determine whether certain genes in cancer may be abnormal. When a gene is abnormal this is called a mutation. Most mutations in cancer cells are not inherited (passed down from parents) but happen after birth in the cancer itself. Most cancers have many mutations. Some of these mutations are important for the cancer cells to survive while others are not. The goal of this study is test cancer for certain mutations using leftover tumor tissue from a previous surgery or biopsy. Participants will also be asked to provide a tube of blood cheek (also known as a buccal) swab, or a saliva sample that contains normal genes for comparison.
The purpose of Part B of this study is to:
Understand how genetic changes in tumor effect the chance of responding to experimental cancer treatment. Understand how the genes in the tumor change overtime in response to targeted cancer treatment.
Details
| Condition | Solid Tumors, Hematologic Cancers |
|---|---|
| Treatment | molecular profiling of tumors, Clinical Germline Analysis |
| Clinical Study Identifier | NCT01775072 |
| Sponsor | Memorial Sloan Kettering Cancer Center |
| Last Modified on | 7 October 2022 |
How to participate?
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.
Learn moreIf you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.
Learn moreComplete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.
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