Embryo Implantation After Induced Endometrial Injury

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  • participants needed
  • sponsor
    Instituto Valenciano de Infertilidad, IVI VALENCIA
Updated on 23 April 2022
embryo transfer


Some studies have revealed that an induced endometrial injury could improve embryo human implantation in patients with implantation failure.

The purpose of this study is to determine whether the induced endometrial injury could be beneficial for regular patients undergoing IVF


Endometrial induced injury has been suggested that could improve embryo implantation in cases of patients with recurrent implantation failure. The mechanisms that induce that improvement remain unknown.

We want to analyse if the endometrial induce injury could be useful in cases of standard patients who require assisted reproductive techniques.

For that purpose we will start a randomized controlled trial with the ideal background in implantation in ART, the egg donation programme.

Condition Sterility
Treatment Scratching
Clinical Study IdentifierNCT01955356
SponsorInstituto Valenciano de Infertilidad, IVI VALENCIA
Last Modified on23 April 2022


Yes No Not Sure

Inclusion Criteria

-44 aged women
-29.9 Kg/m2
st or 2nd fresh embryo transfer ( egg donation)
or 2 blastocysts available
written agreement
> or = 6 mms endometrial thickness

Exclusion Criteria

Premature ovarian failure
Endometrial pathology
Insufficient endometrial development
Mullerian malformations
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