Embryo Implantation After Induced Endometrial Injury

  • STATUS
    Recruiting
  • days left to enroll
    27
  • participants needed
    600
  • sponsor
    Instituto Valenciano de Infertilidad, IVI VALENCIA
Updated on 23 April 2022
embryo transfer

Summary

Some studies have revealed that an induced endometrial injury could improve embryo human implantation in patients with implantation failure.

The purpose of this study is to determine whether the induced endometrial injury could be beneficial for regular patients undergoing IVF

Description

Endometrial induced injury has been suggested that could improve embryo implantation in cases of patients with recurrent implantation failure. The mechanisms that induce that improvement remain unknown.

We want to analyse if the endometrial induce injury could be useful in cases of standard patients who require assisted reproductive techniques.

For that purpose we will start a randomized controlled trial with the ideal background in implantation in ART, the egg donation programme.

Details
Condition Sterility
Treatment Scratching
Clinical Study IdentifierNCT01955356
SponsorInstituto Valenciano de Infertilidad, IVI VALENCIA
Last Modified on23 April 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

-44 aged women
-29.9 Kg/m2
st or 2nd fresh embryo transfer ( egg donation)
or 2 blastocysts available
written agreement
> or = 6 mms endometrial thickness

Exclusion Criteria

Premature ovarian failure
Endometrial pathology
Insufficient endometrial development
Hydrosalpinx
Mullerian malformations
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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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