Postoperative Conformal Radiotherapy for Stage II-III B Type Thymoma

  • STATUS
    Recruiting
  • End date
    Jul 24, 2022
  • participants needed
    210
  • sponsor
    Chinese Academy of Medical Sciences
Updated on 24 January 2021
thymic neoplasm

Summary

The purpose of this study is to determine whether postoperative conformal radiotherapy are effective in the treatment of Masaoka stage II-III B type thymoma.

Description

The role of postoperative radiotherapy in thymoma is controversial. Some retrospective studies were for the radiotherapy, but others were against. However, more inherent biases existed in these trials. Resection, Masaoka stage and pathology were widely accepted as the prognostic factors for thymoma. Furthermore, the frequency of local failure after radical resection was still high in Masaoka stage II-III B type thymoma. With the conformal technique appearing, conformal radiotherapy can escalate the dose without increasing the risk of normal tissue toxicities.

Details
Condition Thymoma, Thymoma, Thymomas, thymic neoplasm
Treatment Radiotherapy
Clinical Study IdentifierNCT02014805
SponsorChinese Academy of Medical Sciences
Last Modified on24 January 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Age 18-75, Zubrod-ECOG-WHO 0-2, the interval of surgery to radiotherapy < 2months, Masaoka stage II-III and WHO B type thymoma

Exclusion Criteria

No second primary tumor, no serious comorbidity, no neoadjuvant anticancer treatment, no adjuvant chemotherapy
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