Last updated on July 2018

Plasma Biomarkers P-DAC V1


Brief description of study

This is an exploratory, translational, non-interventional and multi-centre clinical study. The aim of the study is to identify predictive plasma biomarkers of response to chemotherapy in PDAC.

Detailed Study Description

This study will involve two cohort groups, all patients involved will have PDAC.

Cohort A: Target is 80 resectable PDAC patients who will receive standard treatment of chemotherapy +/- radiotherapy

Cohort B:

  • Cohort B1 = Target is 80 unresectable locally advanced PDAC patients who will receive standard treatment of chemotherapy +/- radiotherapy.
  • Cohort B2 = Target is metastatic PDAC patients who will receive standard treatment of chemotherapy +/- radiotherapy.

Control patients: Target is 50, with acute pancreatitis admitted to hospital for observation/treatment.

Blood samples will be taken at the following time points:

  • prior to resection, whenever feasible for cohort A
  • prior to CT, for both cohort A and B
  • during CT, for both cohort A and B
  • follow-up, approximately every 3 to 6 months for two years for cohort A

Clinical Study Identifier: NCT02050997

Contact Investigators or Research Sites near you

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MinYuen Teo, Dr

Adelaide Meath National Childrens Hospital
Tallaght, Ireland
0.7miles
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Ray McDermott

Beacon Hospital
Bracken Rd, Sandyford Industrial Estate, Ireland
6.4miles
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Liam Grogan, Prof

Beaumont Hospital
Dublin, Ireland
6.41miles
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Ray McDermott, Dr

St Vincent's Hospital
Dublin, Ireland
6.41miles
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