Last updated on February 2018

Bilateral Prefrontal Modulation in Alcoholism


Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Drug abuse | Executive Dysfunction
  • Age: Between 18 - 60 Years
  • Gender: Male or Female

Inclusion Criteria:

  • patients between the age of 18 and 60 years;
  • met criteria for alcohol dependence according to the Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV), as determined by clinical evaluation;
  • in stable clinical condition with no need for inpatient care;
  • able to read, write, and speak Portuguese; and
  • no severe withdrawal signs or symptoms at baseline.

Exclusion Criteria:

  • a condition of intoxication or withdrawal due to a substance other alcohol;
  • unstable mental or medical disorder or substance abuse or addiction other than alcohol dependence, except nicotine and/or caffeine;
  • a diagnosis of epilepsy, convulsions, or delirium tremens during abstinence from alcohol;
  • a previous history of drug hypersensitivity or adverse reactions to diazepam or other benzodiazepines and haloperidol;
  • any contraindication for electrical brain stimulation procedures such as electronic implants or metal implants;
  • suspected pregnancy for female participants;
  • any contraindication for magnetic resonance procedures such as electronic implants, metal implants, claustrophobia, or permanent make-up or tattoo received within the previous 3 months;
  • the presence of vascular, traumatic, inflammatory, or tumor injuries detectable by CT examination.

Recruitment Status: Open


Brief Description Eligibility Contact Research Team


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