The Effects of Mycophenolate Mofetil (MMF) on Renal Outcomes in Advanced Immunoglobulin A (IgA) Nephropathy Patients

  • End date
    Dec 15, 2021
  • participants needed
  • sponsor
    Fan Fan Hou
Updated on 15 March 2021
mycophenolate mofetil
renal failure
glomerular filtration rate
antihypertensive drugs
immunoglobulin a
primary iga nephropathy


The study is to evaluate the effect of Mycophenolate Mofetil compared with losartan alone on time to doubling of serum creatinine or the onset of end stage renal disease in patients with advanced IgA nephropathy who are treated with the maximal tolerated daily dose of losartan.The study will also assess the effects of MMF compared with losartan alone on the changes of urine albumin excretion and the changes in estimated glomerular filtration rate.

Condition IgA nephropathy, Glomerulonephritis, Autoimmune disease
Treatment mycophenolate mofetil, losartan
Clinical Study IdentifierNCT01854814
SponsorFan Fan Hou
Last Modified on15 March 2021


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