The China Pulmonary Thromboembolism Registry Study

  • STATUS
    Recruiting
  • End date
    Dec 31, 2025
  • participants needed
    15000
  • sponsor
    China-Japan Friendship Hospital
Updated on 25 January 2021
thrombosis
clot
deep vein thrombosis
thromboembolism
pulmonary embolism
embolism
venous thrombosis
pulmonary thromboembolism
dvts

Summary

Epidemiological data on pulmonary embolism (PE) in China needs to be updated and reported. The China Pulmonary Thromboembolism Registry Study (CURES) is designed to provide the cross-sectional spectrum and chronological trends of PE in China, as well as to reveal the intrinsic etiology and pathogenesis of the disease. The CURES is an ongoing large prospective multicenter registry, which was originally initiated in January 2009 via enrolling suspected or confirmed PE or PE with DVT (deep venous thrombosis) patients and assessed their in-hospital outcomes from 100 medical centers in the China PE-DVT network. As of July 2011, in order to determine the PE-relevant short-term outcomes, enrolled participants were followed-up for at least three months in a longitudinal manner. Since August 2016, with the launch and development of precision medicine research scheme in China, the main principle investigators of CURES decided to collect enrolled patients' blood samples with regular follow-ups every three or six months for at least two years (for long-term outcomes). The study protocol has been approved by the China-Japan Friendship Hospital ethics committee, and all collaborating centers received approvals from their local ethics committee. All patients provided written or verbal informed consent to their participation.

Details
Condition Pulmonary Disease, Lung Disease, Venous Thrombosis, Deep Vein Thrombosis, Venous Thrombosis, Venous Thromboembolism, Venous Thromboembolism, Pulmonary Embolism, Pulmonary Embolism, Thromboembolism, Thromboembolism, Thrombosis, Thrombosis, Blood Clots, Blood Clots, Lung Disease, Deep Vein Thrombosis, deep venous thrombosis, lung embolism
Treatment No intervention
Clinical Study IdentifierNCT02943343
SponsorChina-Japan Friendship Hospital
Last Modified on25 January 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Objectively confirmed symptomatic PE or PE with DVT patients aged 18 years or above
Be able to provide written or verbal informed consent to participation

Exclusion Criteria

Younger than 18 years
Participation in a therapeutic clinical trial with an unknown drug
Inability for at least three-month follow-up since July 2011
Suspected PE or PE with DVT patients admitted to the hospital whereas without confirmed medical evidence
Patients with a history of PE or DVT readmitted to the hospital for examination or treatment however with no evidence of acute episode or recurrence
Withdrawal or lack of informed consent
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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