Last updated on May 2018

The Hasselt APPendicitis Immunology and Environmental Cohort STudy


Brief description of study

The Hasselt Appendicitis Immunology and Environmental Study (HAPPIEST) aims at characterizing factors that influence the development and severity of acute appendicitis. In a cohort of 300 patients and 300 controls, environmental factors as well as genetic make-up of the innate immune system, focusing mainly on pattern recognition, will be analyzed in order to gain insight in their relative importance in the pathology of appendicitis. Furthermore, populations of micro-organisms present in the gut of patients will be characterized, and the interaction between relevant micro-organisms and the innate immune system will be analyzed.

Clinical Study Identifier: NCT02391675

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Toon H Peeters, MSc

Jessa Ziekenhuis
Hasselt, Belgium

Inge C Gyssens, MD PhD

Radboud University Medical Center
Nijmegen, Netherlands

Recruitment Status: Closed


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