Last updated on March 2019

Effects of Nocturnal Non-invasive Ventilation on Energy Expenditure in Patients With Severe Chronic Obstructive Pulmonary Disease


Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Energy Metabolism | Non-invasive Ventilation | Chronic Obstructive Lung Disease | Pulmonary Rehabilitation
  • Age: - 100 Years
  • Gender: Male or Female

Inclusion Criteria for Intervention group:

  • chronic obstructive pulmonary disease stage IV
  • indication for the use of a nocturnal non-invasive ventilation (according to the German guidelines Schoenhofer et al. 2008)
  • patient has not yet used non-invasive ventilation at all or inadequately (less than 3 hours per day)

Exclusion Criteria for Intervention group:

  • acute exacerbation of chronic obstructive pulmonary disease
  • severe heart failure
  • body-mass-index >35 m/kg
  • fever

Inclusion Criteria for control group:

  • chronic obstructive pulmonary disease stage IV (- healthy volunteers are also eligible for the sub-trial of this study to validate night movement accuracy of an activity monitor)

Exclusion Criteria for control group:

  • acute exacerbation of chronic obstructive pulmonary disease
  • indication for the use of a non-invasive ventilation
  • severe heart failure
  • body-mass-index >35 m/kg
  • fever

Recruitment Status: Open


Brief Description Eligibility Contact Research Team


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