Pulmonary hypertension (PH) is defined as a pulmonary arterial mean pressure (meanPAP) 25 mmHg measured in the right heart catheterization.
There are different forms of PH defined in the classification of Dana Point 2008.
PH is diagnosed with right heart catheterization but there are other non invasive methods which can be used for screening like the echocardiography, stress echocardiography and cardio pulmonary exercise testing. In the diagnosis process and in the follow up of PH patients biomarkers like NTproBNP are helpful. There are no specific biomarkers for the disease which can make the diagnosis process easier and predict prognosis.
The systematic data collection in a data base provides better information about patients in daily routine and clinical studies as well as in the design of new studies.
In this study the investigators want to collect clinical data of PH patients and controls in a database as well as blood samples in a biobank. The combination of anamnestic and clinical data and biomarkers should provide a better characterization of our patients and should improve the analysis of the disease development of different PH forms and therapeutic aspects.
After given informed consent patients' data are entered in a database at different time points. The database includes parameter of several invasive and non-invasive investigations like right heart catheterization (RHC), echocardiography, ECG, pulmonary function tests, cardiorespiratory exercise testing, 6-minute walk test, computed tomography, MRI, polysomnography, blood gas analysis and laboratory data as well as demographic data of the patients.
The blood samples are taken during routine punctuation and are stored in our biobank.
Condition | Pulmonary Hypertension, Effects of Chemotherapy, Anemic Cancer, Habit Reversal, Surviving Abuse, Abdominal Surgery, Primary Insulin Hypersecretion, Open Heart Surgery, Cancer Prevention, Stasis Dermatitis, Nerve Injury, Pseudobulbar Affect, Joint Injuries, Chronic Pelvic Pain, Pelvic Adhesions, Mental Disability, Dental Filling, Low Testosterone, Myopic Macular Degeneration, Spinocerebellar Disorders, Complicated Grief, Serial Evaluation of Ductal Epithelium, Renal Anemia, Chronic Renal Anemia, Recurrent Pregnancy Loss, Testotoxikose, Functional Dyspepsia, Pulmonary Arterial Hypertension, Infantile Fibrosarcoma, Severe Premenstrual Symptom, Partial Medial Meniscectomy, Memory Problems, Gambling Problems, Cancer Treatment, Indikation: Diabetes - Typ II, Spine Athroplasty, Catheter Complications, Late Infantile Neuronal Ceroid Lipfuscinsosis, Cancer Prevention, Surviving Abuse, Joint Injuries, Abdominal Surgery, Mental Disability, Pelvic Adhesions, Low Testosterone, Dental Filling, Habit Reversal, Complicated Grief, Chronic Pelvic Pain, Gambling Problems, Myopic Macular Degeneration, Nerve Injury, Severe Premenstrual Symptom, Stasis Dermatitis, Pulmonary Arterial Hypertension, Open Heart Surgery, Recurrent Pregnancy Loss, Effects of Chemotherapy, Renal Anemia, Functional Dyspepsia, Catheter Complications, Serial Evaluation of Ductal Epithelium, Chronic Renal Anemia, Cancer Treatment, Anemic Cancer, Spinocerebellar Disorders, Pseudobulbar Affect, Spine Athroplasty, Indikation: Diabetes - Typ II, Partial Medial Meniscectomy, Primary Insulin Hypersecretion, Testotoxikose, Infantile Fibrosarcoma, Late Infantile Neuronal Ceroid Lipfuscinsosis, Memory Problems |
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Clinical Study Identifier | NCT01607502 |
Sponsor | Medical University of Graz |
Last Modified on | 27 January 2021 |
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