Last updated on February 2020

COsegregation of VARiants in the BRCA1/2 and PALB2 Genes

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Breast Cancer | BRCA2 gene | Ovarian Cancer | Recurrent Ovarian Cancer | PALB2 | Genes | BRCA1 gene
  • Age: Between 18 - 100 Years
  • Gender: Male or Female

Inclusion Criteria:

Index cases:

  • A person carrying a BRCA1 or BRCA2 or PALB2 variant class 3 or 4, present and selected in the families of UMD-BRCA1/2 or PALB2 national database of genetic group and cancer (GGC Unicancer) which identifies changes in BRCA1, BRCA2 and PALB2 genes of all French laboratories.
  • Age 18 years.
  • Signed written inform consent "index case"

Related parties:

  • Everything related to an index case, diagnosed with breast cancer or ovarian cancer.
  • Any related case of a free index, selected by the investigators, according to family structure and the degree of related compared to the index case
  • Age 18 years
  • Signed written inform consent "Related selected"

Exclusion Criteria:

  • Minors
  • Persons deprived of liberty or under guardianship (including curators).
  • Absence of signed written inform consent

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

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