Follow-up of a Cohort of Patients With Aortic Valve Bicuspidia

  • End date
    Jul 18, 2025
  • participants needed
  • sponsor
    Centre Hospitalier Universitaire, Amiens
Updated on 18 July 2021


The aortic valve bicuspidia (BVA) is a congenital condition corresponding to the presence of 2 sigmoids instead of 3. This is the most common cardiac congenital anomaly affecting 0.5 to 2% of the population The general rule. BVA may be associated with structural damage to the ascending aorta, which exposes BVA patients to a risk of developing ascending aortic aneurysm and acute aortic accidents. Recent data from the literature have revealed that the natural history of BVA is marked by a possible development towards significant valvulopathy and / or an ascending aortic aneurysm often requiring surgical treatment. However, the natural history of bicuspid disease remains poorly understood and the prognostic factors for progression to severe valvulopathy and / or aneurysmal dilatation of the ascending aorta remain to be determined.

Condition Bicuspid Aortic Valve, Aortic Valve, Bicuspid
Treatment Study the natural history of bicuspid
Clinical Study IdentifierNCT03139786
SponsorCentre Hospitalier Universitaire, Amiens
Last Modified on18 July 2021


Yes No Not Sure

Inclusion Criteria

All patients examined in the echocardiography laboratory whose objective examination was a bicuspid valve of the aortic valve
Bicuspidia may be formerly known

Exclusion Criteria

Refusal to participate
Patients who had already undergone bicuspid surgery or ascending aorta before being examined at the echocardiography laboratory
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