Usefulness of Serum Pepsinogen and Gastrin as the Predictive Biomarker of Atrophic Gastritis Intestinal Metaplasia and Gastric Cancer in Korea

  • STATUS
    Recruiting
  • End date
    Dec 22, 2023
  • participants needed
    108
  • sponsor
    Yonsei University
Updated on 22 January 2021

Summary

It is well-known that atrophic gastritis is a major risk factor for gastric cancer, which leads to variations in the serum levels of gastrin, pepsinogen (PG) I, and PGII. We want to assess the effects of age, sex, and Helicobacter pylori status on pepsinogen (PG) level for atrophic gastritis and whether gastric atrophy based on the PG test would be improved after H. pylori eradication.

Details
Condition Atrophic gastritis, gastric atrophy
Treatment pepsinogen and gastrin
Clinical Study IdentifierNCT02184910
SponsorYonsei University
Last Modified on22 January 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

over 19 years
the patients who have gastrointestinal discomfort or get esophagogastroduodenoscopy (EGD) for health check up
the patients who got the procedure, endoscopic submucosal resection (ESD) for early gastric cancer

Exclusion Criteria

gastrectomy history
advanced gastric cancer (impossible to get the gastrectomy)
Helicobacter eradication history
the patients who have chronic disease
cancer patients except gastric cancer within 6 months
who cannot perform this study according to research's decision
who have bleeding tendency (ex. taking antiplatelet agent, low platelet count or abnormal coagulation time)
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

0/250

Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider

Loading...

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 

 • 

Private

Reply by • Private
Loading...

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.
Loading...

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note