Last updated on February 2018

Systemic Therapies for Pediatric Atopic Dermatitis


Brief description of study

While many patients with atopic dermatitis (eczema) can be managed with topical creams and treatments for itch, some children have such severe, long-standing disease that they need treatment with oral medications that decrease the ability of the immune system to react. However, there is not enough information on the proper use of these medications or how well they work compared with each other. The current study looks at the response of children treated with these medications to provide this information and improve their use.

Detailed Study Description

Severe and/or refractory cases of atopic dermatitis (AD) can require systemic immunosuppressive therapy for disease control, yet there are few studies regarding the appropriate use of these drugs for pediatric AD and even less data comparing them. The current observational study will observe the effect of these therapies on children with moderate to severe atopic dermatitis as they are treated. These drugs being observed will be cyclosporine, azathioprine, mycophenolate mofetil, and methotrexate.

Clinical Study Identifier: NCT01447381

Contact Investigators or Research Sites near you

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Lawrence Eichenfield, MD

Rady Children's Hospital
San Diego, CA United States
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Jeffrey Sugarman, MD

University of California, San Francisco
San Francisco, CA United States
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Amy Paller, MD

Children's Memorial Hospital
Chicago, IL United States
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Recruitment Status: Open


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