Last updated on October 2018

Combining MRI Steatosis Assessment and Transient Elastography to Improve Liver Fibrosis Diagnosis in Non Alcoholic Fatty Liver Disease


Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Non Alcoholic Fatty Liver Disease
  • Age: Between 18 - 100 Years
  • Gender: Male or Female

Inclusion Criteria:

  • Patients older than 18 years old
  • For which a liver biopsy is indicated for NAFLD according to current guidelines
  • Presenting with at least one of the metabolic syndrome criteria:
  • BMI > 25 kg/m and/or Waist circumference 94cm for men / 80cm for women
  • Fasting glucose > or = to 5,6 mmol/L or diabetes / or lowering glucose treatment
  • Blood pressure 130/85 mmHg / or treatment
  • Triglycerides than 1,7 mmol/L
  • HDL-C than 1 mmol/L (men), 1,3 mmol/L (women) /or lipid lowering treatment
  • Affiliated to medical care insurance
  • Having signed informed consent for participating in the study

Exclusion Criteria:

  • Associated other chronic liver disease : infectious, auto immune, genetic
  • Alcohol consumption higher than 21 standard unit per week for men, or 14 standard unit for women;
  • Steatosis inducing treatment: steroids, amiodarone, methotrexate, tamoxifen
  • History of bariatric surgery
  • Contra indication to MRI (pace maker, metallic foreign body, claustrophobia)
  • Persons subject to major legal protection (safeguarding justice, guardianship, trusteeship), persons deprived of liberty.

Recruitment Status: Open


Brief Description Eligibility Contact Research Team


Volunteer Sign-up

Sign up for our FREE service to receive email notifications when clinical trials are posted in the medical category of interest to you.