Comparison of the Breast Tumor Microenvironment
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- STATUS
- Recruiting
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- End date
- Dec 31, 2024
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- participants needed
- 30
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- sponsor
- Columbia University
Summary
The goal of the project is to identify a molecular signature of tumor stroma from "normal" adjacent breast tissue obtained prospectively at the time of breast conserving surgery before and after receiving intraoperative radiation therapy (IORT) in subjects that have luminal A and triple negative breast cancer. IORT is considered as being standard of care.
Description
There is evidence that the normal tissue around a tumor plays a role in determining how the tumor behaves, including how it responds to treatments and how likely it is to recur.
Details
| Condition | Breast Cancer, Metastatic Triple-Negative Breast Cancer, Triple Negative Breast Cancer, Chronic Diarrhea, Skin Wounds, Chronic Shoulder Pain, Injection Port, Peripheral Arterial Occlusive Disease, Brain Function, Primary Immunodeficiency, Near-Sighted Corrective Surgery, Breast Cancer - HER2 Positive, Diet and Nutrition, Razor Bumps (Pseudofolliculitis Barbae), Vaginal Atrophy, Anal Dysplasia, Hormone Receptor Positive Malignant Neoplasm of Breast, Recurrent Respiratory Papillomatosis, Pediatric Health, Adverse Effects, Drugs |
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| Treatment | Blood sample collection, Breast tissue collection |
| Clinical Study Identifier | NCT03165487 |
| Sponsor | Columbia University |
| Last Modified on | 2 September 2021 |
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