Last updated on October 2018

Blood Pressure Target in Acute Stroke to Reduce hemorrhaGe After Endovascular Therapy

Brief description of study

A randomized, multicenter study comparing two strategies: 1 / standard management of systolic blood pressure according to international recommendations (systolic blood pressure <185 mm Hg) versus 2 / intensive blood pressure management Systolic with a target <130 mm Hg.

Detailed Study Description

Patients will be followed for 3 months:

  • inclusion after reperfusion: clinical evaluation with NIHSS (National Institute of Health Stroke Score) score, measurement of blood pressure.
  • within 24 hours after reperfusion: blood pressure measurements
  • at 24 hours: measurement of blood pressure (T0 + 24 h and evaluation of the NIHSS score.
  • Between 24 and 36 hours :cerebral scan (assessment of hemorrhagic transformations and cerebral infarction volumes). For some centers: Cerebral MRI without injection between H24 and H36
  • 72 hours after reperfusion: Cerebral scanner in case of hyperdensity on the initial scanner
  • 3 months after reperfusion: disability assessment by Rankin score

Clinical Study Identifier: NCT03160677

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Hopital Foch

Suresnes, France
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Hopital Lariboisi re

Paris, France
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CHU Bic tre

Le Kremlin-Bicêtre, France
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Recruitment Status: Open

Brief Description Eligibility Contact Research Team

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