Evaluation of Xiaflex: Trial of Effectivenss iN Dupuytren's

  • participants needed
  • sponsor
    McMaster University
Updated on 21 May 2022
Achilleas Thoma, MD MSc FRCSC
Primary Contact
St. Joseph's Healthcare (861.8 mi away) Contact
+9 other location
dupuytren's contracture
palmar fasciectomy


This is a prospective, multi-centre, pragmatic randomized controlled trial to compare both the clinical effectiveness and cost-effectiveness of collagenase injections (CI) versus limited palmar fasciectomy (LPF) to determine if collagenase is a superior treatment in terms of improved quality of life and reducing recurrence of the disease without serious complications. Since collagenase injections are costly it is also important to know if this novel intervention is cost-effective from the patient, Ministry of Health and societal perspectives.

Condition Dupuytren's Contracture, Dupuytren's Disease, Dupuytren's Disease, dupuytren disease
Treatment collagenase injection, limited palmar fasciectomy
Clinical Study IdentifierNCT02725528
SponsorMcMaster University
Last Modified on21 May 2022

Similar trials to consider


Browse trials for

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 



Reply by • Private

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note