Last updated on April 2019

The Effects of Antipsychotic Drugs on Brain Metabolism in Healthy Individuals

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: healthy
  • Age: Between 21 - 50 Years
  • Gender: Male or Female

Inclusion Criteria:

  • Age: 21-50 years old
  • Male or female
  • Without psychiatric diagnosis according to a structured psychiatric interview (SCID)
  • Without history of a psychotic disorder among parents, siblings, or children

Exclusion Criteria:

  • Significant medical or neurological illness
  • Diagnosis diabetes mellitus, uncontrolled hypertension, severe hypotension, coronary artery disease, metabolic syndrome, glaucoma, liver impairment, decreased renal function, respiratory disorders, peptic ulcer disease (absolute and relative contraindications to use of antipsychotic drugs)
  • Body mass index (BMI) over 30
  • Taking any other medications, including over the counter supplements with the exception of oral contraceptives for women
  • Pregnancy. Females of child-bearing age must be using an effective contraceptive method
  • History of smoking, substance abuse or dependence
  • Contraindication to MR scan (claustrophobia, cardiac pacemakers, metal clips and stents on blood vessels, artificial heart valves, artificial arms, hands, legs, etc., brain stimulator devices, implanted drug pumps, ear implants, eye implants or known metal fragments in eyes, exposure to shrapnel or metal filings, other metallic surgical hardware in vital areas, certain tattoos with metallic ink, certain transdermal patches, metal-containing IUDs)
  • Medical condition that would prevent blood draws

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

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