Receiving Modified Chemotherapy Followed With Radical Resection After Neoadjuvant Chemotherapy

  • STATUS
    Recruiting
  • End date
    Aug 4, 2023
  • participants needed
    60
  • sponsor
    Peking Union Medical College Hospital
Updated on 4 March 2021

Summary

For patients undergoing postoperative therapy for locally advanced gastric cancer after neoadjuvant chemotherapy, we assessed the utility of graded histologic regression of <50% as the criterion of treatment change. Sixty patients will be enrolled to randomize into two groupsreceiving modified chemotherapy and receiving the original chemotherapy.

Description

For patients undergoing postoperative therapy for locally advanced gastric cancer after neoadjuvant chemotherapy, we assessed the utility of graded histologic regression of <50% as the criterion of treatment change. Sixty patients will be enrolled to randomize into two groupsreceiving modified chemotherapy and receiving the original chemotherapy. Overall survival and disease-free survival will be observed between two groups.

Details
Condition Locally Advanced Gastric Cancer
Treatment Paclitaxel/DDP, XELOX/SOX
Clinical Study IdentifierNCT03322969
SponsorPeking Union Medical College Hospital
Last Modified on4 March 2021

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