Last updated on April 2019

The Role of Stem Cells on Immune Cells in the Development of Cardiovascular Diseases

Brief description of study

An observational pilot proof-of-principle study. 15 patients with significant coronary artery disease and 15 matched controls. To investigate whether long-term activation of the innate immune system, named 'trained innate immunity', occurs at the level of the bone marrow progenitor cells in patients with significant coronary artery disease and whether this correlates with the proinflammatory phenotype of monocytes.

Clinical Study Identifier: NCT03172507

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Department of cardiology, CWZ

Nijmegen, Netherlands

Department of cardiology, Radboudumc

Nijmegen, Netherlands

Recruitment Status: Closed

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