Intraductal Secretin Stimulation Test: What Is the Proper Collection Time?

  • STATUS
    Recruiting
  • days left to enroll
    70
  • participants needed
    36
  • sponsor
    Indiana University
Updated on 1 September 2021

Summary

The aim is to evaluate the peak secretory flow rates and bicarbonate concentrations as determined by a 30 minute intraductal secretin stimulation test in patients with a low likelihood of pancreatic pathology and to compare these data to those obtained from our historical patients with suspected chronic pancreatitis. These will be patients in which inadvertent pancreatic cannulation occurs during therapeutic endoscopic retrograde cholangiopancreatography (ERCP) for biliary indications . All study subjects will receive a 5 day follow-up phone call. Enrollment goal is 36 subjects.

Details
Condition Endoscopic Retrograde Cholangiopancreatography
Treatment Human Secretin for injection 16 mcg
Clinical Study IdentifierNCT03263481
SponsorIndiana University
Last Modified on1 September 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Male or female patients 18 years of age referred to Indiana University Health, University Hospital for ERCP for a biliary indication, at the discretion of the treating MD (e.g. suspected common bile duct stone, initial post-liver transplant evaluation, suspected or confirmed cholangiocarcinoma, suspected primary sclerosing cholangitis -- see exclusion criterion #12)

Exclusion Criteria

Pregnant woman or breast feeding
Age <18 years
Patient unable to give informed consent
Patient with a history of pancreatic surgery
Patient with a history of pancreatic cancer
Patient with a history of acute or chronic pancreatitis
Patient with radiographic evidence of acute or chronic pancreatitis on CT, MRCP, or EUS
Patient with a current or prior history of average daily alcohol consumption of greater than 60 g per day for more than 2 years
Patient with a history of cigarette smoking greater that 20 pack-years
Patient with a history of pancreas divisum
Evidence of chronic pancreatitis on pancreatogram during ERCP
ERCP for an isolated biliary indication with previous biliary sphincterotomy or for biliary stent exchange, when pancreatic entry should easily be avoided by the endoscopist
History of allergy or adverse reactions to secretin
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

0/250

Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider

Loading...

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 

 • 

Private

Reply by • Private
Loading...

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.
Loading...

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note