Feasibility and Safety of Umbilical Cord Blood Transfusion in the Treatment of Neonatal Cerebral Ischemia and Anemia

    Not Recruiting
  • participants needed
  • sponsor
    Mononuclear Therapeutics Ltd.
Updated on 22 January 2021
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The study is to investigate the feasibility and safety of autologous umbilical cord blood transfusion to treat the newborn infants with presence of clinical indications of neonatal hypoxic-ischemia encephalopathy (HIE) and anemia. Umbilical cord blood (UCB) is collected following labor and is transfused intravenously within 48 hours after the birth. Newborn infant without UCB available recieves the standard care will be enrolled as control group.

Following the autologous UCB transfusion in the study group or standard care in the control group, HIE subjects will be followed for 2 years for survival and neurodevelopmental outcomes and anemia subjects will be followed for 6 months to assess the survival and change of hematocrit and hemoglobin levels.

Condition Hypoxic Brain Damage, Neonatal anemia, Hypoxia Neonatal, Cerebral Ischemia of Newborn
Treatment Standard Care, umbilical cord blood (UCB), autologous umbilical cord blood (UCB)
Clinical Study IdentifierNCT03352310
SponsorMononuclear Therapeutics Ltd.
Last Modified on22 January 2021

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