Last updated on April 2019

Study to Evaluate Efficacy and Safety of PF-04965842 in Subjects Aged 12 Years And Older With Moderate to Severe Atopic Dermatitis

Brief description of study

B7451012 is a Phase 3 study to evaluate PF-04965842 in patients aged 12 years and older with a minimum body weight of 40 kg who have moderate to severe atopic dermatitis. The efficacy and safety of two dosage strengths of PF-04965842, 100 mg and 200 mg taken orally once daily, will be evaluated relative to placebo over 12 weeks of study participation. Eligible patients will have an option to enter a long-term extension study after completing 12 weeks of treatment.

Clinical Study Identifier: NCT03349060

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Clinical Research Center of Alabama, LLC

Birmingham, AL United States

Clinical Science Institute

Santa Monica, CA United States

Forward Clinical Trials, Inc.

Tampa, FL United States

Meridian Clinical Research

Savannah, GA United States

MediSearch Clinical Trials

Saint Joseph, MO United States

Lynn Health Science Institute

Oklahoma City, OK United States

Texas Dermatology and Laser Specialists

San Antonio, TX United States

Virginia Clinical Research, Inc.

Norfolk, VA United States

Somerset Skin Centre

Troy, MI United States

TCR Medical Corporation

San Diego, CA United States

Arlington Research Center, Inc.

Arlington, TX United States

Pace Dermatology Associates

Lakewood, WA United States

MultiCare Allenmore Hospital

Tacoma, WA United States

Pace Dermatology Associates

Tacoma, WA United States

Dawes Fretzin Clinical Research Group, LLC

Indianapolis, IN United States

Dawes Fretzin Dermatology Group, LLC

Indianapolis, IN United States

Olympian Clinical Research

Largo, FL United States

Spectrum Medical Imaging

Maroubra, Australia

Innovaderm Research Inc.

Montreal, QC Canada

Diex Research Sherbrooke Inc.

Sherbrooke, QC Canada

Sinclair Dermatology

East Melbourne, Australia

Bridge Road Imaging

Richmond, Australia

CRU Hungary Ltd.

Miskolc, Hungary

Tufts Medical Center

Boston, MA United States

Henry Ford Medical Center, New Center One

Detroit, MI United States

Emeritus Research

Camberwell, Australia

Skin and Cancer Foundation Inc

Carlton, Australia


Carlton, Australia

Kirk Barber Research

Calgary, AB Canada

Dr. Chih-ho Hong Medical Inc

Surrey, BC Canada

The Centre for Dermatology

Richmond Hill, ON Canada

York Dermatology Center

Richmond Hill, ON Canada

Fachklinik Bad Bentheim

Bad Bentheim, Germany

Queensland X-Ray

Upper Mount Gravatt, Australia

Veracity Clinical Research Pty Ltd

Woolloongabba, Australia

SKiN Centre for Dermatology

Peterborough, ON Canada

Research Toronto

Toronto, ON Canada

Lynderm Research Inc

Markham, ON Canada

Institute for Skin Advancement

Calgary, AB Canada

Wiseman Dermatology Research Inc.

Winnipeg, MB Canada

Rhode Island Hospital

Providence, RI United States

The Royal Childrens Hospital

Parkville, Australia

Dermedic Jacek Zdybski

Ostrowiec Swietokrzyski, Poland

MUSC SCTR Research Nexus Clinic and Laboratory

Charleston, SC United States

Lekarna Na Vaclavskem namesti

Kutna Hora, Czechia

Oregon Health & Science University

Portland, OR United States

Lekarna U sv. Ignace

Praha 2, Czechia

Mayfair Diagnostics

Calgary, AB Canada

Lekarna Fakultni Nemocnice Ostrava

Ostrava - Poruba, Czechia

Fakultni Nemocnice Ostrava, Kozni oddeleni

Ostrava - Poruba, Czechia

The Dudley Group NHS Foundation Trust

Dudley, United Kingdom

Universit tsklinikum M nster

Münster, Germany

Recruitment Status: Closed

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