Evaluating MMPs in Burns

  • STATUS
    Recruiting
  • participants needed
    60
  • sponsor
    University of Florida
Updated on 1 March 2021
injuries
scald

Summary

The objective of this study is to determine whether our chemical assay can be used to reliably predict graft take or failure in patients undergoing autologous skin grafting for treatment of acute burn injury.

Description

This is an observational pilot study of patients treated at UF Health Shands Burn Center adult service. This is a study to determine the predictive value of quantifying concentrations of specific MMPs. Coupling this with a specialized collection sample collection system and a calibrated fluorimetry allows for the rapid assessment of MMP concentrations. This assay has been validated as a predictor of failed wound healing in a published clinical study involving chronic open wounds.

Details
Condition Trauma, Burns, Burns and Burn Infections, Thermal Burns, Thermal Burn, Thermal Injury, Wounds, thermal injuries, burn injuries
Treatment Graft, Graft
Clinical Study IdentifierNCT03148977
SponsorUniversity of Florida
Last Modified on1 March 2021

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