Last updated on April 2019

Anagre Cap. in Patients With High-Risk Essential Thrombocythemia

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Age: Between 19 - 100 Years
  • Gender: Male or Female

Inclusion Criteria:

  • Patients with essential thrombocythemia according to WHO 2008
  • Any of the following as high-risk patient
  • Over 60 years old
  • >100 X 10^4/ul of platelet count
  • increased more than 300K of platelet count in 3 months
  • Hypertension, diabetes, past history of thromboembolic bleeding

Exclusion Criteria:

  • Patients with an adverse drug reaction or intolerability to anagrelide
  • Any of the following cardiac abnormalities;
  • Complete left bundle branch block on ECG
  • Patients using a pacemaker
  • Patients with a family history of congenital QT prolongation syndrome or known QT prolongation syndrome
  • Currently, there is no clinically uncontrolled ventricular or atrial tachycardia
  • Clinically significant bradycardia (<less than 50 per minute)
  • History of clinically proven myocardial infarction and unstable angina within 3 months
  • Pregnant women, nursing mothers

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

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