Letrozole in Clomiphene Resistant Infertile Women With Polycystic Ovarian Syndrome

  • STATUS
    Recruiting
  • participants needed
    80
  • sponsor
    Assiut University
Updated on 3 June 2023
cardiovascular disease
metformin
letrozole
polycystic ovary syndrome
clomiphene
endometrial carcinoma

Summary

Polycystic ovary syndrome accounts for the vast majority of anovulatory symptoms and hyperandrogenism in women. The diagnosis of Polycystic ovary syndrome has life-long implications, with increased risk for infertility, metabolic syndrome, and type 2 diabetes mellitus, and possibly for cardiovascular disease and endometrial carcinoma. Polycystic ovary syndrome is diagnosed in adolescents with otherwise unexplained, persistent hyperandrogenic anovulatory symptoms that are inappropriate for age and stage of adolescence. It should be considered in any adolescent girl with a chief complaint of hirsutism, treatment-resistant acne, menstrual irregularity, acanthosis nigricans, and/or obesity

Details
Condition Infertility, Female
Treatment Letrozole, letrozole plus metformin
Clinical Study IdentifierNCT03135301
SponsorAssiut University
Last Modified on3 June 2023

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